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Institutional User Agreements
… of sequencing data for synthesis. This agreement, required by the DOE for all work performed in its User Facilities, is … execute a 2024 version .  The recent updates were approved by the DOE to address the DNA Synthesis program. When fully … to a new commercial institution requires approval by all parties. … After your proposal is approved, the …
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A Natural Mechanism Can Turbocharge Viral Evolution
… step in the deadly dance between a virus and microbial cell is an embrace. For a virus with a “head-tail” … ago, a team discovered a group of viruses that had in their genomes a surprising tool: a “diversity generating … DGR could mutate the virus’ tail fiber proteins, and thereby allow them to embrace different cells. Since that …
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Natural Prodcast Episode 22: Alison Narayan
… can it actually turn over? ALISON NARAYAN: So that’s an excellent question. I think that we need enzymes with good … in depth. So some of these that were initially identified by Russell Cox, like [INAUDIBLE]– DAN UDWARY: Explain to my … thanks so much for talking to us today. This is really an excellent conversation. I’m so happy we did this. ALISON …
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A Plant Root Atlas for Tracking Developmental Trajectories
A collaborative team led by Geoffrey Schiebinger at the University of British … the  Arabidopsis root, profiling nearly 100,000 single root cells and combining the information with previously … work was  recently published in the journal  Developmental Cell and provides a community resource that could help …
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Ancient Algae Reveal Secrets of Plant Evolution
… plants conquer land over 600 million years ago. The Science By studying the genes of land plants’ closest algal … land. Key gene groups involved in stress tolerance and multicellularity enabled plants to develop complex structures and … Laboratory (Berkeley Lab), scientists sequenced the genomes of four  Zygnematophyceae algae, which were isolated …
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Community Science Program
… synthesis, metabolomics and analysis will be performed by the JGI at no cost to the user. … All proposals first undergo technical review by JGI staff, while the DOE ensures that they meet DOE … review , proposals are evaluated and placed in rank order by the reviewers. The ranked proposal list, along with a …
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2021 JGI Proposal Call Brings New Investigators into Community Science Program
Brassicales Genome Initiative. Brassicales is represented by more than 4,700 species, and the proposal focuses on … range of environments. A similar proposal focused on diatom genomes from  Thomas Mock of the University of East Anglia … of Rutgers University is interested in understanding how unicellular red algae (Cyanidiophyceae) have adapted thrive in …
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Toward More Efficient Artificial Photosynthesis
… cycle. The Science Chloroplasts are the factories in plant cells. Using photosynthesis, they take raw materials … to convert them into energy that is then stored. A team led by researchers at the Max Planck Institute (MPI) for … a platform that mimics chloroplast function within a cell-sized system. The Impact Photosynthesis harnesses …
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JGI Early Career Researchers Featured in mSystems Special Issue
… metagenomics. One approach uses fluorescence-activated cell sorting (FACS) to sort cells into several small pools … processes. A third approach steps away from reconstructing genomes directly from the environment and focuses on … global ecological and environmental processes, especially by modifying host cell metabolism and altering cell fitness. …
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Natural Prodcast Episode 9: Roger Linington
Biodiversity Groups, and it’s this great program funded by the National Institutes of Health and the National … carefully at these as being candidates siderophores. Or for cell-cell signaling or for, you know, other other roles here. So …
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Plotting a Model for Virus-Host Warfare Deep Below Ground
The battle waged below the Earth’s surface is reconstructed by combining a study of microbial communities (metagenomics) … nitrogen, but the viruses that infect Altiarchaea cause the cells to burst. This action triggers subsurface carbon … of countering multiple attempts at virus infections. Their genomes include short DNA sequences that code for CRISPR …
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JGI@25: From Life at the Extremes to Editing Genomes
… for her work on CRISPR-Cas9, technology described by the Nobel Foundation as having “a revolutionary impact on … is a pioneer in metagenomic studies, recovering microbial genomes from biofilm samples at the Richmond Mine in Iron … scoutRNA Is Required for Some Type V CRISPR-Cas Systems Mol Cell. 2020 Aug 6;79(3):416-424.e5. doi: …
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