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Microfluidic-based mini-metagenomics enables discovery of novel microbial lineages from complex environmental samples
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
… of the world’s soil carbon. The process to harvest energy-generating peat from these boggy wetlands produces an estimated 5% of annual … was theorized that sex determination was possibly driven by genetics, or even temperature. By sequencing the genome, …
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Biodesign
… into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, nutrient … platform enables users to validate hypotheses generated from mining genomic data by designing and assembling …
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Mining Metagenomes for Cas Proteins
… Cas14 proteins discovered from JGI’s IMG/M database and biochemically characterized at … Genomics Institute.  The Science Researchers report the discovery of miniature Clustered Regularly Interspaced Short … The ability to accurately edit genomes (that is, repair gene mutations, and either delete or add genes in a precise …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… determine mutualism or parasitism between some archaeal hosts and their hitchhikers. The Science Within the archaeal … Horonobe Underground Research Laboratory, Hokkaido, Japan. From samples of both environments, they used fluorescence  … Then, using metagenomes and metatranscriptomes generated by the U.S. Department of Energy (DOE) Joint …
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Nigel Mouncey
… 27-year history. He has a wealth of managerial experience from almost 20 years in the Industrial Biotechnology private … Dr. Mouncey has a long-standing interest in microbial genetics that started with his education and carried forward … Dr. Mouncey directed R&D teams that focused on the discovery, development and commercialization of novel …
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The Power of One, Amplified
… single cell genomics by collecting nearly 500 single cells from a single low diversity hot spring sediment sample. … that species specific sets of single cells harbored mobile genetic elements that were missed within paired metagenome … of single cell sequencing to assess the variation within natural microbial populations. Each of the three sequencing …
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How Maize Makes An Antibiotic Cocktail
… that maize synthesizes these compounds via clear, straight pathways, entailing the function of more than a dozen … buck. The research team reports that transferring just four genes encoding these enzymes to another plant, such as  … ability make zealexins, and harnessed gene expression data from these lines to identify genes associated with zealexin …
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JGI@25: A Single Cell, Myriad Microbial Discoveries
… genomic information using minute quantities of DNA derived from individual environmental cells. The proof of principle … team reported the first closed and finished genome derived from an uncultured bacterial single cell – a symbiont of the green sharpshooter. In 2012, single cells isolated from the microbes found in the oil plume from Deepwater …
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Tanja Woyke
… After studying the mechanism of action of antifungal natural products and their derivatives during her Ph.D. in … a Research Scientist position in 2007, she switched gears from metagenomics to single-cell genomics, which is now her … at the University of California, Merced's School of Natural Sciences since 2015. Prospective users with specific …
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Analysis of twelve genomes of the bacterium Kerstersia gyiorum from brown-throated sloths (Bradypus variegatus), the first from a non-human host.
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Analysis of 4,664 high-quality sequence-finished poplar full-length cDNA clones and their utility for the discovery of genes responding to insect feeding
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