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Gut Fungi: Unexpected Source of Novel Chemicals
… and help them digest their last leafy meal. In their evolutionary history, these fungi branched off early from aerobic … called natural products . Yet, combing through the genomes of four anaerobic fungal species has revealed, for … clearly have unexpected chemical potential. … This research project was supported by a grant from Santa Barbara Cottage …
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User Programs
… is no cost to the user and no granting of funds.   Proposal Call FICUS CSP Large Scale CSP New Investigator CSP Functional Genomics Status CLOSED CLOSED ONGOING ONGOING Who Should Apply? Investigators with research projects that integrate the expertise and capabilities of …
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The Chlamydomonas Genome Project, version 6: reference assemblies for mating type plus and minus strains reveal extensive structural mutation in the laboratory.
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The YNP Metagenome Project: Environmental Parameters Responsible for Microbial Distribution in the Yellowstone Geothermal Ecosystem
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Programs & Platform Leads
As an Integrative Genome Science User Facility, the JGI plays a leadership role in enabling the frontiers of research related to DOE’s missions in bioenergy, carbon …
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Calculating the Costs of Multiple Switchgrass Gene Copies
… at the University of Texas (UT) at Austin, the HudsonAlpha Institute for Biotechnology (HudsonAlpha), and the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … two copies of the genome , which can have pronounced ecological and evolutionary consequences. A previous study …
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Gene Expression: From On-Off Switch to Dial
Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science … researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … glycerol and galactose. Although they are historically well-studied, Alper’s team discovered new gene targets …
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How Filamentous Fungi Sense Food
… of California, Berkeley used a multi-omics approach to reconstruct and model gene regulatory pathways used by the … researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … proposal akin to the Encyclopedia of DNA Elements (ENCODE) project, which is aimed at determining the activity, …
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Uncovering Novel Genomes from Earth’s Microbiomes
Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … methods in the past decade, researchers have uncovered genomes for just a small fraction of Earth’s microbial … hope JGI and other institutions continue to do this kind of projects.” The work also used resources of the  National …
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Green Algae Reveal One mRNA Encodes Many Proteins
Gene expression in eukaryotes was long held to be monocistronic – that … a little deeper, and realized what was really happening,” recalled Sean Gallaher, a research scientist in Sabeeha … Laboratory, the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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Tanja Woyke
After studying the mechanism of action of antifungal natural products and their derivatives … Woyke pursued her postdoctoral research at the DOE Joint Genome Institute in 2004. The main object of her research … and an Adjunct Associate Professor at the University of California, Merced's School of Natural Sciences since 2015. …
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The Biota Project: A Case Study of a Multimedia, Grassroots Approach to Scientific Communication for Engaging Diverse Audiences.
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