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Engagement Webinar: Utilizing long-read sequencing for metagenomics and DNA modification detection
… on how the JGI employs single-molecule, long-read DNA sequences to aid with genome assembly and transcriptome … metagenomes can I submit?  How deeply are metagenomes sequenced? A:  For the next call ( CSP New Investigator ), … count toward the 1Tb cap. PacBio metagenomes are currently sequenced without pooling, which yields ~ 180 Gb of data per …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… Group. Many of these bacterial and archaeal genome sequences have been generated using techniques that the JGI … Over the years more than 3,400 genomes have been sequenced from curated DSMZ isolates, for which quality DNA … collapsed, while these issues are not commonly seen with reference isolates. “For secondary metabolite discovery in …
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Evolution of a Fungal Gene Expression Regulator
… in fungi. The Science Changing an A, C, T or G in a genome sequence can lead to changes in protein structures and … development. Summary With the aim of producing at least one reference genome for every family of fungi, the 1000 Fungal … Using new sequencing technologies for producing both reference genomes and epigenomics, researchers are …
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
… the hummocks or the more water-logged hollows below. These preferences affect their growth rates, decomposition, and … Laboratory, and the HudsonAlpha Institute for Biotechnology sequenced sphagnum  genomes from plants selected by a team … and others that preferred the hollows. Those genome sequences showed not only that the sex of a sphagnum plant …
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The More the Merrier: Making the Case for Plant Pan-genomes
… the JGI’s  Community Science Program , the team generated reference genomes for  B. hybridum and  B. stacei , as well … the fact that the genetic information in a single reference genome is insufficient. “We really have to … B. hybridum accessions produced infertile F1 descendants (first offspring of the parents), posing the question if they …
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Len Pennacchio
… of human epilepsy and subsequently generated one of the first mouse models for this common neurological disorder. In … Program Defining the vast landscape of gene regulatory sequences in the human genome. Understanding how variation in regulatory sequences influences human disease/biology. Assessing and …
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JGI Scientists Pen Genome Watch Articles
… Institute in the UK — a nonprofit that was founded to help sequence the human genome. Today, the Sanger Institute … to (meta)genomics, and at least one of the papers they reference should be hot off the press. She tells prospective … the article comes out — about two months after the first draft. Woyke has so far selected the authors of these …
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Mapping the Earth’s Hidden Fungal Kingdom
… about 200,000 fungal species have been named. Among those sequenced, roughly half of all genes have completely unknown … for prediction of fungal lifestyles based on genome sequences.” The Fungal Knowledge Gap The fungal kingdom … species lies an even thornier problem: The genomes already sequenced don't adequately capture the vast nature of fungal …
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JGI-USCCN Strain Sequencing Opportunity
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A chromosome‐scale reference genome of trifoliate orange (Poncirus trifoliata) provides insights into disease resistance, cold tolerance and genome evolution in Citrus
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The Chlamydomonas Genome Project, version 6: reference assemblies for mating type plus and minus strains reveal extensive structural mutation in the laboratory.
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Comparative Analyses of Four Reference Genomes Reveal Exceptional Diversity and Weak Linked Selection in the Yellow Monkeyflower (Mimulus guttatus) Complex
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