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Streamlining Regulon Identification in Bacteria
… in Streptomyces coelicolor . The Impact As an integrative genome science user facility, connecting genes to functions … which Mouncey leads. RIViT-seq is a three-step process. The first step is the in vitro transcription assay. The second … the 5’-ends by 5’-end sequencing, from which those promoter sequences recognized by a given sigma factor are inferred. …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
… trace its origins, the researchers engaged the DOE Joint Genome Institute (JGI), with support of the US Department of … of millions of trees in California alone. With the genome sequence in hand, the UC team led the charge to develop … SOD infection analysis. These collaborations represent the first-ever large-scale “citizen science” project to generate …
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Matt Blow
… Dr. Blow joined the JGI in 2009, and currently heads the Genome Analysis group. In this role he supervises the Genome Assembly, QA/QC, and User Support Analysis teams. … on computational and experimental approaches to study genome regulation in human and other vertebrate genomes. …
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JGI Accepts 17 Proposals for Community Science Program
… (CSP) call of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … international collaboration that produced the reference genome sequence for Eucalyptus grandis. Accessing recently burned …
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Virus Discoveries that Keep Getting Bigger
… Sequence-based studies — from metagenomics to single-cell … Nucleocytoviricota , these giant viruses boast larger genomes than many bacteria. Until recently, understanding of … culture-independent approaches to gain insight into the  genomes of giant viruses. In a new review, researchers from …
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
… enabled by the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … of methanogenesis, with metagenomic support from the JGI. First they were able to identify the potential for … the original methanogens were, but they were discovered by genome sequencing, which is a much less biased approach to …
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Whole metagenome sequencing and 16S rRNA gene amplicon analyses reveal the complex microbiome responsible for the success of enhanced in-situ reductive dechlorination (ERD) of a tetrachloroethene-contaminated Superfund site
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From Intern to Published Scientist: The Journey of a JGI-UC Merced Intern
… determination. Rhondene Wint, an alumna of the DOE Joint Genome Institute (JGI)-UC Merced internship program and … publication in Molecular Biology and Evolution . “It’s my first publication and it feels so rewarding,” Wint said. For … applications, Wint also developed and tested a gene sequence-based predictor of gene expression levels using …
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Genomic Signatures for Sedimentary Microbial Utilization of Phytoplankton Detritus in a Fast-Flowing Estuary
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Divergent Genomic Adaptations in the Microbiomes of Arctic Subzero Sea-Ice and Cryopeg Brines
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A unified catalog of 204,938 reference genomes from the human gut microbiome
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Acquisition and Adaptation of Ultra-small Parasitic Reduced Genome Bacteria to Mammalian Hosts
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