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… further demystify biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not … survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … luminescens and its secondary metabolites work could yield new tools for pest control. Secondary metabolites are highly …

… a computer could use to conduct a similar type of search in microbial and metagenomic databases. In this case, the … and a unique chronic infection cycle. “We’re not sure why we systematically manage to miss them; maybe it’s due to … first worked on a reference dataset that included genome sequences known to be affiliated with the Inoviridae. “What …

Miscanthus  sequence offers insights into benefits of polyploidy and perenniality. The Science A reference genome sequence and genomic toolkit for the perennial grass … of rapidly growing plants whose biomass can be renewably converted into energy or biofuels. Although a member …

… technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … is particularly interested in understanding how, when and why microbes decide to produce which metabolites. … BS, … H, Mouncey NJ. New keys to unlock the treasure trove of microbial natural products. Nat Rev Microbiol. 2021 …

A special issue of Synthetic Biology celebrates research enabled by the JGI … and synthesis work. This is where the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office … large-scale functional screens for characterization of new enzymes and use the data we generated to train machine …

… for researchers to request the capabilities and expertise of multiple DOE National User Facilities in one research … being lack of relevance to DOE mission areas.  Initiate a new LOI by logging into the   EMSL User Portal  and clicking … samples of the spatial, temporal, taxonomic (environmental, microbial, plants, invertebrate, and vertebrate), and …