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Yasuo Yoshikuni
… Dr. Yasuo Yoshikuni has been head of the DNA Synthesis Science Program since 2015. The mission … program is to harness the power of DNA synthesis, strain engineering, and biosystems design for DOE-mission-relevant discovery and applications. This … at the JGI. Click to learn more about the program's areas of focus, major initiatives and more.  …
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Direct pathway cloning of the sodorifen biosynthetic gene cluster and recombinant generation of its product in E. coli
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Improving the Cacao Genome and Phytozome
… to climate change and devastating fungal infections. That’s why Mars, Inc., a maker of chocolate for more than 100 years and one of the world’s largest … through the Cacao Genome Database project. The genome sequence was assembled by the plant team at the  HudsonAlpha …
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Protocols
… protocols provided by JGI and the JGI user community below for DNA preparation tools, high molecular-weight DNA … Tips for High Molecular Weight DNA extraction: …
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User Support
… The JGI Project Management Office carries out a number of activities to facilitate … work and outline roles and responsibilities resulting in a formal Statement of Work (SOW). All work performed at the JGI is initiated via the Work Initiation …
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Four Researchers Join JGI User Executive Committee
… State University, Jonathan Eisen of the University of California, Davis, and Michael Köpke of Lanzatech are the latest … functional encyclopedia building on GEBA) and in microbiome engineering.  Köpke is the Chief Innovation officer at … technology. His research foci have been genomics, metabolic engineering, synthetic biology of non-model …
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Microbiome engineering for sustainable agriculture: using synthetic biology to enhance nitrogen metabolism in plant-associated microbes
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Metabolomics
… functional genome annotation, improves understanding of the role small molecules play in diverse biological … of new molecules and pathways. The JGI Metabolomics Platform delivers rich metabolite profiles from diverse … products At JGI, in-depth molecular profiles are generated for metabolites extracted from a variety of experimental …
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Team Science Reveals Important Protein in Poplar
… Knockout experiments showcase potential for engineering bioenergy crops The Science Scientists at … Described as the “DOE Tree,” poplar is considered one of the  Flagship Plants for the U.S. Department of Energy … II, a U.S. DOE Office of Science User Facility operated for the DOE Office of Science by Brookhaven National …
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W. Berkeley Kauffman
… Berkeley is responsible for receiving and processing user samples. His R&D work focuses on the development of new applications utilizing a variety of technologies to … in the areas of metagenomics, single-particle genomics, and metabolic engineering. …
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Taking Stock of the Known and Unknown Microbial Space
… in sequencing technologies have led to an abundance of microbial genomes becoming available to the global … genomic biodiversity. Using publicly available genome sequence data generated over the past three decades, their … the microbial diversity we know about, and proposes a path forward to curate and cultivate what is still unknown.  “We …
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
… New studies show methanogenesis is not exclusively for Euryarchaeota. Atmospheric levels of methane, a potent … only microorganisms capable of methanogenesis —  it’s the metabolic process these little makers rely on to survive. … global carbon cycle and greenhouse gas dynamics, and the engineering of new, optimized methane-making microbes. In …
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