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Metabolomics
… this identification, metabolomics enables functional genome annotation, improves understanding of the role small …
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From Competition to Cooperation
… lineages. The Science By comparing 135 fungal sequenced genomes, researchers were able to carry out a broader … lineages. To learn why, researchers analyzed 135 fungal genomes representing major fungal families, including those for which there were previously no genomes of symbiotic species available: 73 saprotrophs and …
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Getting to the Bottom of Fungal Functions Across Earth’s Forests
… researchers have leveraged data from the 1000 Fungal Genomes project to form new connections between fungal … and developed new tools to map that soil RNA to fungal genomes.  The U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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Len Pennacchio
In 2003, Dr. Pennacchio joined the DOE Joint Genome Institute and has focused on applying … joint appointments as a Deputy Director at the DOE Joint Genome Institute, Senior Scientist at Lawrence Berkeley … vast landscape of gene regulatory sequences in the human genome. Understanding how variation in regulatory sequences …
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A One-Stop Shop for Analyzing Algal Genomes
… genes of more than 100 algae. The Science Interested in the genomes of algae? You now have one place where you can … and enthusiasts to look deep into more than 100 algal genomes, compare them, and visualize supporting experimental … In part because of this evolutionary diversity, algal genomes can be incredibly complex and difficult to sequence …
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Finding the Fermenters
… including the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … browser that allows other researchers to study the genomes and predict the metabolic abilities of these … GOLD and IMG data portals to get information about the genomes and genes of the organisms on the list. They also …
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Better Genome Editing for Bioenergy
… included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User … a team of researchers sought to disrupt every gene in the genome with CRISPR-Cas9 in order to interrogate each one’s … a pool of sgRNA sequences: six for every gene in the genome. The JGI  DNA Synthesis Science team synthesized …
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Picking Up Threads of Cotton Genomics
Analysis reveals cotton genome stability across global lineages . Come harvest time, … darwinii are the others. All of these cotton lineages have genomes approximately 2.3 billion bases or Gigabases (Gb) in size, and are hybrids comprised of cotton A and cotton D genomes. A multi-institutional team including researchers at …
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Jeremy Schmutz
Mr. Schmutz’s involvement with the DOE Joint Genome Institute dates back to 1997, when he was working for the Stanford Human Genome Center, now the HudsonAlpha Institute for … Hossain, J. T., Lovell, J. T.., et al. 2023. JGI plant gene atlas: an updateable transcriptome resource to improve …
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A Complex Confection Decoded: Sugarcane Reference Genome
… was the last major crop without a reference quality genome and now crop researchers can work toward advancing … accounts for 80% of global sugar production. A reference genome for the sugarcane cultivar R570 has been  published … a crop. The Impact In providing a reference sugarcane  genome , the JGI provides foundational genetic information …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… help solve energy and environmental challenges.   The Human Genome Project began in 1990 when the U.S. Department of … studying Chromosome 5, which contains about 6% of the human genome . They discovered genes linked to conditions such as … Chromosome 19, which contains about 2% of the human genome. They were interested in genes involved in repair of …
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David Goodstein
… gene models in support of JGI’s contributions to the Human Genome Project, he began developing larger comparative … Plant Comparative Analysis group, and is responsible for genome annotation, comparative analysis and data … 35 (2), 644-672 A Sreedasyam et al., 2023. JGI Plant Gene Atlas: an updateable transcriptome resource to improve …
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