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Virus Discoveries that Keep Getting Bigger
… new review, researchers from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science … to provide a perspective on giant virus diversity, and how sequencing and bioinformatics have sped up the study of … spans from very large virions (700 nm in diameter) to much smaller virions (120 nm in diameter). Across the …
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CSP Functional Genomics
… and ‘omics capabilities to enhance understanding of gene and genome function, particularly those not readily … will be externally peer-reviewed for scientific merit, DOE mission relevance , proposed data usage by the … and track record of the applicant.  Learn about the general review process or find details on the internal …
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Gene Expression: From On-Off Switch to Dial
… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The … and included researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science … were previously missed in knock-out screens. These results show that this singular library synthesized by JGI was …
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Novel soil bacteria possess diverse genes for secondary metabolite biosynthesis
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Duplications and losses of genes encoding known elements of the stress defence system of the Aspergilli contribute to the evolution of these filamentous fungi but do not directly influence their environmental stress tolerance
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Genome-wide identification of bacterial plant colonization genes
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Elucidating Bacterial Gene Functions in the Plant Microbiome
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JGI@25: Expanding Metagenomics to Capture Viral Diversity
… we have revisited a number of notable achievements that showcase our collaborations and capabilities to enable great … and a specific microbial host to replicate. Sequencing genetic material directly from samples sidesteps these challenges, since it doesn’t require this kind of lab culture. Beginning in the …
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Expanding Virophage Diversity
… Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells … viruses. Almost all known virophage genomes share only four genes in common: major and minor capsid proteins (MCP and … the team concluded, “we provide a global analysis of the diversity, distribution, and evolution of virophages.” Lead …
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Getting to the Bottom of Fungal Functions Across Earth’s Forests
… — skills that matter increasingly as the climate warms. However, these are complicated interactions to untangle. … soil RNA to fungal genomes.  The U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science … the world. These tools give researchers a way to access much more information about fungi in these environments. …
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New and Improved: Eucalyptus Reference is Now Accessible
… Eucalyptus grandis reference genome that has been widely adopted. The new genome assembly resolves both haplotypes, … greater contiguity, meaning the genome is reconstructed in much larger and more complete segments. This allows for more … of the genus. Understanding all the gene variants and how they interact with each other could help tree breeders …
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Mutant phenotypes for thousands of bacterial genes of unknown function
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