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Complete Genome of Oil-Rich Alga Reveals Ideal Platform for Bioengineering
… Streamlined genome with precise gene targeting transforms oil-producing alga into a powerful … optimized for industrial oil production. The organism uses specific chemical tags on DNA  to control which genes are … (9203). RJC was supported for his work on  Auxenochlorella genome sequencing and assembly in Berkeley, in part, through …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
… previously unseen — is, in fact, a microscopic water mold, genetically related to such aquatic species as diatoms and … trace its origins, the researchers engaged the DOE Joint Genome Institute (JGI), with support of the US Department of … was released to the public in a highly-cited 2006 publication in the journal Science . This provided a …
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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… illumination to produce a signal, making them useful in a wider range of environments. This new technology enables … at the University of California, Berkeley and the Joint Genome Institute, a DOE Office of Science User Facility, … resonance energy transfer (BRET)-based biosensors. In general, CSL biosensors produce large signal changes, but …
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Complete plastid genome sequences suggest strong selection for retention of photosynthetic genes in the parasitic plant genus Cuscuta
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Salicylic acid modulates colonization of the root microbiome by specific bacterial taxa
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Gene Expression: From On-Off Switch to Dial
… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more nuanced … researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … The work conducted by the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility, is …
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Mutant phenotypes for thousands of bacterial genes of unknown function
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and his team  … engineering system that allows scientists to conduct genome-wide screens and explore biosynthetic pathway. Thus far, the … domesticate some 60 strains, inserting into them a genetic sequence that acts as a “landing pad.” Mouncey adds, …
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A Collaboration to Improve Plant Genome Annotations Across Species
… To provide broad plant genomic capabilities, the DOE Joint Genome Institute works in partnership with the HudsonAlpha … led a team that  recently published work on the JGI Plant Gene Atlas in  Nucleic Acids Research . The project spans 15 … transcribed from all the genes within a cell or tissue at a specific time or under specific conditions – in over a dozen …
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Model Fern Reveals Insight into DNA Thievery in Ferns
… Open Green Genomes hits milestone with C. richardii The Science Fern … event that occured some 60 million years ago. Massive gene loss, rampant gene duplications, and even more ancient … fern’s distant cousin. Ceratopteris richardii, or C-fern, specifically has been studied in plant research laboratories …
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Axel Visel
… Dr. Visel joined the DOE Joint Genome Institute in 2010. As the Deputy … where he developed novel tools for large-scale in situ gene expression analysis in multicellular organisms. During … our seven science program — their areas of focus, major initiatives and more.  …
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Metagenomic reconstructions of bacterial CRISPR loci constrain population histories
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