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iPHoP: A Matchmaker for Phages and their Hosts
…   To understand virus-host dynamics, computation helps fill in what cultivation can’t. The Science At first, viruses are … to commandeer. For bacteriophage viruses, these hosts are microbes like bacteria, not humans. With metagenomic … Within the domains of archaea and bacteria, millions of  microbes govern ecosystems. These organisms carry out …
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Natural Prodcast Episode 22: Alison Narayan
Hey everyone. Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial Microbiology and Biotechnology (SIMB) Natural …
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Tanja Woyke
After studying the mechanism of action of antifungal natural products and their derivatives during her Ph.D. in Microbiology at the Eberhard Karls … Institute at Caltech Review (Member of Visiting Committee), NASA Exobiology.  … Volland et al. 2022. A centimeter-long …
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Plotting a Model for Virus-Host Warfare Deep Below Ground
…   Visualizing a novel, candidate viral genome found in the deep … ecosystem. The Science Altiarchaea are carbon-fixing microbes and targets of multiple viruses in Earth’s deep … to infect and destroy the host archaea – and how the  microbes resist. The battle waged below the Earth’s surface …
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JGI@25: Following Fungi that Pry Apart Plant Polymers
… 25th anniversary. Over the last year, we’ve been revisiting a number of notable achievements that showcase our … evolved these really tough cell wall materials that keep microbes — and the enzymes that would be produced by … they all process loads of tough plants. Thanks to gut microbes — namely, anaerobic fungi — these animals are able …
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How to Target a Microbial Needle within a Community Haystack
A workflow for capturing the genetic make-up of specific uncultivated microbes from complex environmental samples. The Science A … to first target cells from communities of uncultivated microbes, and then efficiently retrieve and characterize …
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Viruses Reprogram Cells into Different Virocells
Microbial cells infected by viruses undergo metabolic reprogramming. The … infections cause significant metabolic changes in marine microbes, the answer is no. They refer to the infected … changes they’ve undergone. The Impact The number of microbes in, on, and around the planet is an astronomical …
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JGI Early Career Researchers Featured in mSystems Special Issue
In a special issue of mSystems , out May 14, 2019, JGI … outline more targeted approaches to reconstruct individual microbes in an environmental sample beyond the … into several small pools before sequencing to recover rare microbes. The technique was applied to a recent Nature …
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Building Sphagnum Genomic Resources
Sphagnome data would enable researchers’ insights on their potential carbon cycling impact.   The … cycling is a carbon flux regulator since sulfate-reducing microbes prevent methane production by routing the carbon … oxidation. The findings lead them to speculate that these microbes could use the same pathway for either sulfur …
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Pinning Down a Piece of Photosynthesis
By studying the structure and function of a cyanobacterial protein, researchers have new insights into how these ocean … a research scientist at the JGI and Molecular Foundry, and the study’s senior author. In other proteins, two …
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Danielle Goudeau
Danielle operates the single-cell genomics pipeline for JGI collaborators. This work combines custom flow cytometric analysis, cell sorting, genome … flow cytometry protocols for targeted recovery of specific microbes. …
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Notes on the Microbial Diversity of Puerto Nuevo’s Coastline
Puerto Nuevo is a small town along the Baja California coastline in Mexico. While conducting early field studies related … has a number of applications, including pain relief. The microbes in cone snails may be involved in venom activity, … has started, known as the Initiative for Venom Associated Microbes and Parasites. Ul-Hasan credits her JGI-UC Merced …
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