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Computationally Classifying Fungal Lifestyles
Machine learning methods were applied on sequenced fungal genomes to classify gene families. The Science As a proof of … that “taught” a computer how to classify 101 representative genomes of Dothideomycetes, the largest class of fungi, by … to identify data generated in part through the 1000 Fungal Genomes Project, including 55 newly-sequenced species.  The …
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Len Pennacchio
In 2003, Dr. Pennacchio joined the DOE Joint Genome Institute and has focused on applying … joint appointments as a Deputy Director at the DOE Joint Genome Institute, Senior Scientist at Lawrence Berkeley … vast landscape of gene regulatory sequences in the human genome. Understanding how variation in regulatory sequences …
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A Redesign for Yeast’s Genome, Chromosome by Chromosome
To engineer yeast to do more, and understand genomes in general, Jef Boeke, Weimin Zhang (NYU Langone … the goal is to create an entirely human-generated yeast genome. …
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Single Cell Research Group
… in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to … relationships and to provide valuable reference genomes in under-populated areas of the tree of life, as reference genomes are critical to serve as phylogenetic anchors for …
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Frederik Schulz
Dr. Frederik Schulz joined the DOE Joint Genome Institute in 2016 and is leading the New Lineages of … to the JGI user community and supports various user projects in the Microbial Program. In an LDRD-funded … al. 2022. Giant virus biology and diversity in the era of genome-resolved metagenomics. Nature Reviews Microbiology …
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Cataloging the Microbes that Manage the Health of River Systems
Nature paper , researchers describe a dataset of microbial genomes sampled from rivers covering 90% of the watersheds … National Laboratory. The JGI sequenced over 1,000 metagenomes and established standardized sequencing protocols so … collected at each sampling site, were compiled into the Genome Resolved Open Watershed database (GROWdb). The team …
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Natural Prodcast Episode 21: Elizabeth Parkinson
… exposure to working with Streptomyces, learning more about genome mining, as well as isolation and a little bit of … that. JACKIE: So I guess when you get a new organism or a genome, let's say, and you're looking at clusters, is there … BETSY PARKINSON: Sure. JACKIE: If we're looking through a genome, how-- BETSY PARKINSON: Yeah. JACKIE: --what would …
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Natural Prodcast Episode 15: Katherine Duncan
… was really before– or kind of around about when the first genome sequencing was done. But natural products– marine … unprecedented in the terms biosynthetic gene clusters and genome size. And they’re so complex. There’s so much still … awesome. I should point out that we also have a couple of projects in the lab that also work in microalgae as well. So …
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A Grass Model to Help Improve Giant Miscanthus
… of polyploidy and perenniality. The Science A reference genome sequence and genomic toolkit for the perennial grass  … Miscanthus sinensis has been published. Analysis of the genome sequence also provides insights into how the multiple … environments such as poor soils and drought. The reference genome for  M. sinensis,  and the associated genomic tools, …
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Natural Prodcast Episode 9: Roger Linington
… products field as it relates to structure elucidation and genome mining, and how we might start to better connect … and doing medicinal chemistry, doing development of projects on a project-by-project basis. And the more time … a podcast produced by the US Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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Zhong Wang
… analyses and software to enable “grand-scale” scientific projects. These solutions include large-scale genome variants analyses, next-generation transcriptome de novo assembly, metagenome and metatranscriptome assembly, Hadoop based on …
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JGI@25: Roots of a Mutualist Relationship
… energy and environmental challenges. In March 2008, the genome sequence of the forest fungus Laccaria bicolor was … a symbiotic relationship with the poplar, a JGI Flagship Genome and the first tree to have its genome sequenced. Having this first genome sequence of a …
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