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Hey everyone. Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society … enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

… at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … and work within the DOE emission space of bioenergy, carbon cycling, biogeochemistry, bioproducts. So we cannot work on … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger …

The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their … communities contribute to critical processes such as carbon cycling, nutrient cycling, and energy flow. One of the key … comprising the largest public collection of plasmid sequences identified from genomes, SAGs, MAGs, metagenomes …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … more about some of the background and sort of the reasons why we want to do this. And also to provide a little more …

As an Integrative Genome Science User Facility, the JGI plays a leadership role in enabling the frontiers of research related to DOE’s missions in bioenergy, carbon cycling and biogeochemistry. In complement to the Community …

… is focused on genomic science projects that address sustainable biofuel and bioproducts production, leveraging systems-based approaches to unravel functional … and microbial communities, global carbon and nutrient cycling, and biogeochemistry — questions of relevance to …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very …

… strengthens -omics technologies at the JGI by identifying the actual molecules present in an environment that influence system behavior.  Through … play in diverse biological systems, sheds light on nutrient cycling, and leads to the discovery of new molecules and …

Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, … Program aims to generate large datasets to explore sequence-function relationships, advancing the discovery of … Science Group supports researchers exploring how to convert sequence into functional assessments. The team has a …