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… there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger … people, lake sediments. We have microbiomes from different organisms, including the human microbiome. We just really …

… least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … being the standard set of shared reactions that most living organisms share – have together. Obviously that is flawed, … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

FY 2025 DOE Metrics Sequencing Quarter Total Bases (Trillions) Operating Hours Goal Actual Total* Actual % of Goal Goal (hours)** Actual Total Actual % Goal FY 2025 … = 91 days; Actual Operation = 24 days due to significant sequencer downtime related to the shelter-in-place. ††† …

The mission of the Joint Genome Institute is to serve the scientific … … For sequencing projects, once work is under way, raw sequence data is released to NCBI’s Sequence Read Archive on …

… love a challenge, and love the idea of working on harder organisms, with the kinds of challenges that usually lead to … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

… the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very … And so that’s a big collection of natural product-producing organisms that Pfizer, you know, mined for years to try to …

The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … comprising the largest public collection of plasmid sequences identified from genomes, SAGs, MAGs, metagenomes …

You know, at that time, it was just [that] the chemistry of organisms was fascinating to people. And in many ways, the … then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … the common biochemical pathways shared by almost all living organisms. So almost all of these reactions are going on in …

… “Adopt a Genome” is an informal program for faculty to “claim” the JGI’s … work with undergraduates in the analysis and publication of the claimed genome sequences. This opportunity, provided by the Department of …

Plants are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental …