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… of this is based on a really great paper that came out in 2020 where this is all explained in detail, so if you’d like … least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

… capabilities support researchers exploring how to convert sequence into functional assessments. This is done by … design tool  … BOOST provides a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination …

… resequencing, RNA sequencing and epigenomics. Expansion of sequence space:  The JGI generates reference genomes from … of microbial communities based on their metagenome sequence, in the context of reference isolate genomes …

… right? BEN: Yeah, yeah. Well, we are at [10 to the] minus 12 [Molar concentration]- is sufficient to kill cells. So … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very …

… capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA … the minimum is 100 kb, and for metabolomics, at least 22 samples are required. If your proposed request falls … and personnel resources for genomic research and sequence-based science.  Projects include de novo generation …

… this policy) produced through all user projects accepted FY22 and later through the Community Science Program (CSP), … embargo starting at construct or strain delivery.  Detailed sequence information for constructs are made publicly …

… (see Auspice Statement below) for the generation of sequence or metabolomic data, DNA synthesized, and any other … annotation, comparative analysis, and interpretation of sequence, metabolomics, and functional genomics data types … for your proposal using your proposal's WIP ID (ex. 503582). Click on the correct proposal name on your search …

… project by watching Amanda Hurley’s presentation from the 2019 JGI Genomics of Energy & Environment Meeting.] He’s … at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways …

… at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … We don’t want to get a proposal that’s just asking for 20 microbial genomes. That is not a good fit for our annual … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …

… we discussed in the primer podcasts ( part 1 here , part 2 here , and part 3 here ), which you should be able to find … out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk …

We focus our efforts on integrating database mining and sequence design with scaling the production of large, … developing methods for converting digital information from sequence databases into biotechnological or environmental …

… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … to tell a quick story. Looking back, the year was probably 2010, 2011, I was a, uh- actually, I’ve got the t-shirt on … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean …