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… work like ActDES, which is a curated database of actinobacteria for evolutionary studies, and hopefully we can … least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

… more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene … come from all kinds of disparate environments. There’s some marine. There’s some soil samples. There’s human gut …

… focuses on the exploration of secondary metabolites across bacteria, fungi, algae and plants. These molecules, which … reservoir of secondary metabolites produced by bacteria, fungi, algae and plants. These compounds are key to organisms' interactions with their environments and with each other, …

… of microbial metabolism towards a minority of cultivated bacteria, still persists to date. Research Team    … show that the gap between cultivated and uncultivated Bacteria and Archaea has steadily been widening since 2005. … is also reflected in the strongly biased representation of sequenced genomes in the public domain, the bulk of which …

… level. To fully characterize the range of virus-host interactions occurring in microbiomes, these omics data must … viral infection cycle in wild populations of green sulfur bacteria with long standing virus-host interactions. ISME J. 15, 1569–1584. … Single-cell resolution of phage-host interactions …

… chemical compounds that you find in plants, fungi and bacteria, basically all living things. When your crazy Aunt … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … more about some of the background and sort of the reasons why we want to do this. And also to provide a little more …

… of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. … the community so far. But being here and then being at the Marine Natural Products meeting in Ventura where I got to …

… pipelines.  You will receive automated emails as raw sequence data becomes available, and as analysis is …

… the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very … origin is around 30,000 from fungal, and a 40,000 from bacteria. Okay? And among the 40,000 from bacteria, there’s …

… For sequencing projects, once work is under way, raw sequence data is released to NCBI’s Sequence Read Archive on a regular basis, in accordance with JGI’s data release policy.  Interactions with applicants and others who might be …

… in doing so enabled the JGI to be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, …

… And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … has to have a story. And it can be looking for drugs from marine organisms, in which case you get to go to exotic …