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… ,  Science Focus Areas  (SFA) opportunities, and the  Office of Science Early Career Research Program .   If … capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA … 22 samples are required. If your proposed request falls below these thresholds, you will need to utilize a core …

… is actually-- might be better, especially in really low-yielding products. We're interested in some of the … The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain …

… there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … it from an evolutionary standpoint where I really could follow evolution. And I could see a certain time span within … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger …

… See below for examples of successful Letters of Intent to our Community Science Program Large-Scale Call, … to soil carbon storage during simulated range shifts of plant-fungal symbionts … Elucidation of the gene regulatory networks governing terpenoid-mediated … of simplified soil communities with high and low carbon use efficiency across differing moisture …

… analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … associated with microeukaryotes, enhances our understanding of terrestrial biogeochemical cycling and inter-organismal … using single cell approaches. This includes linking strain-level genetic variation to ecological niche …

… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … out, or it’s periodic at least? You get a lot of wind blowing things around that are salts that dry out? Is that … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a …

… when I was three and almost died of an infection following the amputation. So I had this kind of oddball … culture-disconnected. Like we’ll take some soil samples and sequence all the bugs out of that or whatever. And so I was … methicillin-resistant Staphylococcus aureus . Can you share why finding treatments for these microbes is so important? …

… enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … grant. And that having a whole panel of these enzymes allows us to ask the questions which ones express the best in … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh …

… least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … evolutionary forces will be very flexible. They will allow promiscuity and the enzymes are driving the production … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and … and are influenced by microbial partners. We use a variety of genomics-powered tools to study this complexity, … Resident viruses can be found in a myriad of bacterial strains, whereby they can modulate host metabolism, gene …

… DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have … of a colony. This is a zoomed in photo of a really blown up colony of Streptomyces.  ALISON: It’s wild. It kind …

… of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. … It’s anthropomorphizing a little bit here, but it allows us to think about what the quote unquote “purpose” is …