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Products
… as well as target cycle times from sample receipt to completion of standard analysis.  Raw data is provided … sequencing products below. In addition, JGI will submit raw sequence data to  SRA at NCBI once the standard analysis is … analysis Relative abundance profiling of polar (e.g. amino acids, nucleosides, etc) metabolites using normal phase …
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Natural Prodcast Episode 12: Nadine Ziemert
… there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … so far no species or no strains known that really grow in freshwater. But they’re actually pretty orange, and they … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel … November 11, 2022, in Cell Genomics , the team focused on Actinobacteria ( Actinomycetota ), a group of bacteria with … Group. Many of these bacterial and archaeal genome sequences have been generated using techniques that the JGI …
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Single Cell Research Group
Research in the Woyke laboratory focuses on the utility of single-cell methods to access … is also reflected in the strongly biased representation of sequenced genomes in the public domain, the bulk of which … While uncovering the metabolic potential of uncultivated lineages is of high value to establish models and …
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Natural Prodcast Episode 20: Brian Bachmann
And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … that are living there. And we’ve moved recently from actinobacteria now. And we’re focusing much of our efforts …
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Metabolic Network Analysis and Metatranscriptomics Reveal Auxotrophies and Nutrient Sources of the Cosmopolitan Freshwater Microbial Lineage acI
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Metagenome Program
The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural … searches to expand representation of uncultivated microbial lineages. Charting viral ‘dark matter’:   Viruses are … comprising the largest public collection of plasmid sequences identified from genomes, SAGs, MAGs, metagenomes …
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Mission
… capabilities, large-scale data and professional expertise to support the global research community in studies of … in doing so enabled the JGI to be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, … must clearly demonstrate relevance and translatability to freshwater, coastal or terrestrial systems. Additional …
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Natural Prodcast Episode 22: Alison Narayan
… … DAN UDWARY: Hey everyone. Welcome back to Natural Prodcast. This continues the series of interviews … enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh …
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Natural Prodcast Episode 7: Ben Shen
… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very …
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Natural Prodcast Episode 24: Jackie Winter and SMC
… … DAN UDWARY: Hey, everyone! Welcome to the “Self Promotion Episode” of Natural Prodcast. A … is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a …
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RNA-Seq Reveals that Light and Darkness Are Different Stimuli in Freshwater Heterotrophic Actinobacteria
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