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… then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against … a laboratory. Initially, my group really focused on marine actinobacteria. Then we moved into marine proteobacteria. …

… there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … so far no species or no strains known that really grow in freshwater. But they’re actually pretty orange, and they … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger …

… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of … highlights our skewed understanding of microbial metabolism towards a minority of cultivated bacteria, still persists to … is also reflected in the strongly biased representation of sequenced genomes in the public domain, the bulk of which …

… And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … that are living there. And we’ve moved recently from actinobacteria now. And we’re focusing much of our efforts …

… as well as target cycle times from sample receipt to completion of standard analysis.  Raw data is provided … sequencing products below. In addition, JGI will submit raw sequence data to  SRA at NCBI once the standard analysis is complete. Raw … in length, cloned into vector of choice Glycerol stock of sequence verified clone 102/NA DNA Synthesis Constructs …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural … more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene …

… The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural … the Metagenome Program uses several experimental approaches to assess microbial activity across ecosystems.  By studying … communities and their interactions, the Program aims to unlock the fundamental principles that govern ecosystem …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very …

… DAN UDWARY: Hey everyone. Welcome back to Natural Prodcast. This continues the series of interviews … enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh …

… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel … November 11, 2022, in Cell Genomics , the team focused on Actinobacteria ( Actinomycetota ), a group of bacteria with … Group. Many of these bacterial and archaeal genome sequences have been generated using techniques that the JGI …

… required by the DOE for all work performed in its User Facilities, is a legally binding contract.   All User … Appendix identifies the type of work or specific proposal to be covered under the Agreement. The signing official must have the legal authority to commit your institution or organization to the terms and …