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Below is a brief description of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes … pipelines.  You will receive automated emails as raw sequence data becomes available, and as analysis is …

… it’s a little hard to find in print, but we live in the information age and the ebook version is available at most … able to explore DNA sequencing and actually get to the DNA sequence – sequences for the genes that code for the … Something that’s you know …  ALISON: Central! DAN: That’s why they called it that! But for, maybe, people who are less …

… the series of interviews we recorded at the Society for Industrial Microbiology and Biotechnology (SIMB) Natural … enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh …

… research provides insights into microbial diversity and metabolic potential, with implications for energy production, environmental sustainability, and … comprising the largest public collection of plasmid sequences identified from genomes, SAGs, MAGs, metagenomes …

… … DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m … of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. …

… and scientists of secondary metabolism. Welcome back for our second season of Natural Prodcast. This first … more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene …

Marc was the Head of Experimental Genomics there, before he decided to leave for graduate school and pursue his … at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways …

I wanted to tell you about in this introduction. First and foremost, our interview this week is with Professor Brian … And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, …

… and the bacteria and how the chemistry is going back and forth between them is part of what fascinates me about what … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… of secondary metabolism.  DAN: Hey there and welcome back for Episode 8 of Natural Prodcast. This week, we have our … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … Takemura, whose voice you’ll hear in a minute – we work for the US Department of Energy Joint Genome Institute, or … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain …

… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean …