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… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … know everything. These are shared pathways for making amino acids and nucleic acids for DNA and breaking down food so …

Biology is currently experiencing a revolution brought on by rapid developments in … al. (2017) Protein structure determination using metagenome sequence data. Science   355(6322):294-298 Paez-Espino D. et … and uncultured DNA Viruses and retroviruses.  Nucleic Acids Res.  45(D1):D457-D465. Paez-Espino, D. et al. (2016) …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

… … DAN: You’re listening to the US. .Department of Energy Joint Genome … at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of the things I did want to … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against …

…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national user facility located at … JGI consists of around 280 researchers and support staff in the Integrative Genomics Building in Berkeley, …

UDWARY: It’s been a while, but Natural Prodcast is back again for another round of episodes. If you stick around for … at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …

Hey Marcy!  ALISON: Hey Marcy?  MARCY: Hello. How’s it going?  DAN: Good. How are you?  MARCY: Am fine. I live in a … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

The mission of the Joint Genome Institute is to serve the scientific community as … … For sequencing projects, once work is under way, raw sequence data is released to NCBI’s Sequence Read Archive on a regular basis, in accordance with …