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… … DAN UDWARY: You’re listening to the Department of Energy … least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

… … Dan Udwary: You’re listening to the Department of Energy … about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean …

… … DAN: Hey, everybody. Welcome back for another episode of … of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. …

… … DAN: Hey Marcy!  ALISON: Hey Marcy?  MARCY: Hello. How’s it … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… … DAN: You’re listening to the US Department of Energy Joint … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very …

… … DAN UDWARY: You’re listening to the Department of Energy … there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger …

DAN UDWARY: You’re listening to the Department of Energy … more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene …

Below is a brief description of the process needed to prepare and ship samples for sequencing by the JGI. … pipelines.  You will receive automated emails as raw sequence data becomes available, and as analysis is …

JGI Mission As a U.S. Department of Energy Office of Science user … in doing so enabled the JGI to be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, … went on to advance basic science by sequencing scores of microbial species as well as several model organisms and …

… … DAN: You’re listening to the US Department of Energy Joint … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national user facility located at Lawrence Berkeley National …

The Synthetic Biology lab is divided into a DNA synthesis production group and a … DNA synthesis and assembly technologies to the broader community.  We focus our efforts on integrating database mining and sequence design with scaling the production of large, …