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… organisms actually have quite a few antibiotic-resistant genes in there. And so we’re trying to use those as … on that we sequenced the genome. And it has 17 resistant genes on a plasmid that’s actually– it’s pretty scary what … Every tool will tell you something different about the genes or homology to something. There’s a lot– every BGC is …
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… the regulation off, rather than negatively get rid of the genes from their genome. FRANCISCO BARONA-GOMEZ: Exactly … gene cluster starts to merge and expand and accept new genes coming in and out. So, if you start making the … find these definitions useful and we can really start testing and organizing things beyond artificial names. …
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… really, really falls rapidly. But we eventually– after testing all these different zones, we eventually settled in … mining-based approaches are that other than resistance genes, you have no way of knowing of whether or not a … about 20 analogs at this point. And Casey and Nikolaou synthesized the everninomicin at Scripps, I guess, 22 years …
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