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… of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231. Accordingly, the U.S. Government retains a … JGI is not responsible for the contents of any off-site pages referenced. … Disclaimer of Liability … Disclaimer of …

Gluconibacter .  And that got me back a little bit to redox enzymes and looking at gene regulation. And then from there, … in an obvious way. NIGEL MOUNCEY: We did a little bit of metagenome screening work and did find related clusters. But … 30 to September 1st. The link is found all over JGI’s web pages.  DAN: And I will put it in the show notes along with …

Natural Products conference, which took place last January 2020 in San Diego. San Diego, of course, is the “home turf” … marine natural product biosynthesis and at the beginning stages of connecting molecules and genes. And then genomics … might make this molecule and predicting what kind of enzymes might be involved, and then being able to make those …

… inside them. And this was, I think it must’ve been about 2001, maybe, and so it was before smartphones and before … exciting. And why chemistry is so far behind in that stage is it’s still really difficult to do natural products … It’s them that do it. They created the Wiki. They edit the pages. They add the content. They run the Twitter account. …

… and listen to the first two parts ( part 1 is here and part 2 is here ) so you understand what’s happened so far in the … Right. Yeah. DAN: Alright, so a subset of proteins are enzymes. Enzymes are proteins that do chemical reactions. And so …

… found in Yu et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you … ago. Non-ribosomal peptides, remember, are big, complicated enzyme systems that really just exist to pull an amino acid … if an order is uncultured (blue; represented only by metagenome-assembled genomes or MAGs) or cultured (gray; …

Animal Genome XXVII Conference (PAG) takes place January 12-16, 2019, in San Diego, Calif. Representatives from the DOE … on their work. BER Plant Genomic Science Workshop Agenda: 6:20 PM Overview and Joint Genome Institute Plant Program …

… has been a pioneering effort in functional genomics since 2012, with a focus on addressing critical energy and … vision for a sustainable, bio-based economy. … Genome to Enzymes and Pathways focuses on discovering and characterizing enzymes and pathways vital to DOE missions. Using …

… the “Non-Ribosomal Peptide Synthetases” or NRPSs. These are enzyme systems that grab amino acids and stick them together … end, we took an approach that was kind of a simplified metagenome sequencing approach to pick this system apart.  … ended up doing was pursuing with Jacques Ravel, at TIGR, metagenome sequencing, which was very early days for that …