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And when we were talking about definitions around words I made a possibly false statement. I said that I thought that … be the amino acid that is relevant for the synthesis of proteins, and will more often end up in the active site of an … that will actually protect the fungal farms from other fungus that want to take advantage of that resource. So in …
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… another, how do they change then, and why are they really made. I think that’s a question that a lot of people want to … have, right? He was looking for a postdoc and just wrote an email to everyone. And I’m like, oh, I’m looking for … within a community are kind of stable even if the community itself changes a lot. Because you have to be kind of …
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Sure. Definitely. So, I got my PhD with Paul Hergenrother at the University of Illinois at Urbana-Champaign. … So we've also been able to get soils from Purdue campus itself and been able to actually have several undergrads … with the support of my department head, we've actually made a graduate student mental health committee and we're …
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… trained in synthetic chemistry as were you and then made their way into the field of natural products in some … do engineering to improve the physical properties of a protein and make it easier to work with. But sometimes, what … the circumference of that iron, we just have the iron itself litigated into the protein. So we work with Rieske …
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So Brian and I– Brian was the very first recording I ever made practicing for the podcast. And– I did not know what I … of them. So we get them off of wet parts of caves– not dry, dusty, but wet. We like to get them where water is … media. So you could take International Streptomyces Protocol media number 2, ISP2, and dilute it by a factor of …
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… to try to find those things. So, the DNA sequence isn’t itself medicine, but the coding within the DNA codes for proteins that do the chemistry that put molecules together … same kind of way, where we had– aflatoxin is produced by a fungus called Aspergillus . We were mostly working in …
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… world. We used ships. We used land-based marine labs. We wrote cooperative grants with people in other countries. And … try to prove it, was just not known. And the first time I made that comment here at Scripps to our very, very … is a very horrible genus. Because first of all, it’s not a fungus, so why would you have m-y-c-e-s as a suffix? But …
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… to the Department of Energy Joint Genome Institute’s Natural Prodcast, a podcast about natural products and the … Master’s student at the University of Groningen and then I wrote my own grant proposal in the hope that it would get … Dan, we would have contacted you as well and we could have made an even bigger and better for eventually one of …
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… more stuff in the pipeline, including another recording made at SIMB, and any minute now you’ll hear about something … that people work with are actually alpha or gammaproteobacteria. They just have this very restricted niche. … enzymes that can make the signal. You have the signal itself, which again is the acyl homoserine lactone. And then …
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… of biology. DAN: That’s right. BEN: You know, to say, man-made compounds. How can you design a drug, right? You design … national resources. So, you may know the so-called Nagoya protocol, which prevents taking bio-resources from the native … to different species. DAN: Yeah, yeah. BEN: And then for fungus, even more. And of the fungus, we have more than 2600 …
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… this is just the natural products community listening to itself talk, or if we’re finding an audience outside of just … to ensure equitable benefit sharing if any discoveries were made that were of value to the host country. And it had a … could then show that to collaborators and say, “This is a prototype. If you will help, we could do this in a more …
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