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… FY 2026 DOE Metrics Sequencing Quarter Total Bases (Trillions) Operating Hours …     Q4 2026 175     2,208     *Includes Illumina and PacBio sequencing platforms. **Operating Hours target is based on … 185.4% 2,164 2,208 102.0% *Anticipated 50% reduced capacity for Q3 due to Clarity LIMS transition. **Includes …

… enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … [project] with JGI, how many flavin monooxygenases are you sequencing, sort of along that vein, of if you have one or … guess with along that line, with JGI, like how many are you sequencing currently? ALISON NARAYAN: Yeah. So– yeah, with …

… there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … I think. DAN UDWARY: Yeah, and that was a JGI Community Sequencing Project. You’re right, yeah. NADINE ZIEMERT: Yes. … thought because of their structure, and their unique amino acids, and these cross links that they must be made in a …

… which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … percolating through the soil through leaf litter and humic acids and those kind of things close enough. And you can– we …

… and later through the Community Science Program (CSP), Facilities Integrating Collaborations for User Science … For sequencing or metabolomics projects: data are subject to a  … policy and our efforts to see data produced by our facility result in scientific publications. …

… really the same kind of thing. Before the age of genome sequencing, we had to basically break up the pieces of DNA … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene … enzyme systems that really just exist to pull an amino acid out of solution and stick another amino acid or …

… started collaborating with Ben and his group to work on sequencing, synthesis and genome mining technology to help … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … And so, we are developing enabling technology, not only to facilitate the discovery of enediyne, for which, by genome …

… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … to grow. If you hear Nigel talk, he is very interested in sequencing a lot more natural product-heavy culture … I want to help you as that’s what the JGI is, is a “user facility”. And so you don’t have to be a user either for me …

… Institute, or JGI. JGI is a DOE Office of Science User Facility located at Lawrence Berkeley National Laboratory. … – problems that might need special technology for DNA sequencing, genomics, metabolomics, and synthetic biology, … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain …

… The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in … The Metagenome Program focuses on the high-throughput sequencing of microbial communities to uncover the complex … Exploration of phylogenomic novelty: Advances in metagenomic sequencing, assembly and binning have enabled reconstruction …

… Genome Institute is a “Department of Energy user science facility”, and so today what you’re going to hear about are … Science program. It used to actually stand for Community Sequencing Program. Also CSP, same acronym. But as JGI, as a … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …