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… be on a pretty regular schedule for a while. Moving forward, I’m hoping to get a new one out every two weeks. This … started collaborating with Ben and his group to work on sequencing, synthesis and genome mining technology to help … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the …

… For sequencing or metabolomics projects: data are subject to a  … Sequencing and Metabolomics projects …

… bunch of little shows lined up, and I’m really looking forward to getting them out to you all. But for now, here is … really the same kind of thing. Before the age of genome sequencing, we had to basically break up the pieces of DNA … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene …

… you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … took an approach that was kind of a simplified metagenome sequencing approach to pick this system apart.  DAN:  And … the ocean are doing. And specifically, they’re aimed outwards at the behavior of other animals. And so they are …

… be able to share a few more stories from there as we go forward. And Marc’s quickly built up a great body of work, with … the Broad that was looking to develop new methods for DNA sequencing of microbes. And what kept breaking our methods … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways …

… The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in … The Metagenome Program focuses on the high-throughput sequencing of microbial communities to uncover the complex … Exploration of phylogenomic novelty: Advances in metagenomic sequencing, assembly and binning have enabled reconstruction …

… Bill Fenical. And we connected to JGI through the Community Sequencing Program, and they worked with us to sequence two … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against … to correlate chemical to genes. We’re hoping we can move forward and we’re challenging our colleagues at Monterey Bay, …

… at JGI and the other participating facilities, is then forwarded to DOE for final approval.  Following DOE approval, … For sequencing projects, once work is under way, raw sequence … More on Sequencing Projects …

… Science program. It used to actually stand for Community Sequencing Program. Also CSP, same acronym. But as JGI, as a … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these … WILHELM: Yeah. That makes sense. And then, if we fast forward to the end of a successful project, can you talk a …

… by generating data in three overarching categories: DNA Sequencing , DNA Synthesis and Metabolomics .  Many users …

… it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk … everything is funding, right, isn’t it? I thank JGI for sequencing a lot of fungi. But the thing with them – to get … sequence is really cheap. I’ve got colleagues that are sequencing dozens and dozens of fungi, mostly coming out of …

… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … for their contributions just to move this research forward. DAN UDWARY: One of the things in this and the … to grow. If you hear Nigel talk, he is very interested in sequencing a lot more natural product-heavy culture …