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… With collaborative user projects, the JGI’s Plant Program delves into the natural world’s potential to address … The Plant Program advances our understanding of plants’ biological and … including deep learning algorithms for gene annotation and protein folding models, to improve the accuracy of …

… us about forthcoming efforts in paired-omics data sets and seeking to interpret function from BGCs. It’s a long, wide … cluster database, and a tool for predicting natural product structures from genomes. And I was writing grants furiously … primer episode, we talked about genome mining through some metagenome associated genomes. And yes, antiSMASH is …

… The Facilities Integrating Collaborations for User Science (FICUS) call represents a unique … Proposals for the annual FICUS call with EMSL begin with a Letter of … After an LOI is accepted, the researcher then submits a proposal for consideration in the next review cycle. Initiate …

… usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain … bind similar ligands. And so one of-- DAN: OK. The similar proteins are going to bind similar molecules. Yeah, OK. … enzymes show a lot of similarity to them in the primary structure. However, the reaction that they perform is …

… The JGI is leveraging its current partnerships to offer new capabilities and resources to users through a BER … institutions like the JGI, KBase, NCBI, NMDC, EMSL and the Protein Data Bank enables predictive ecosystem biology. The … the JGI has unique access to both expertise and infrastructure to facilitate these efforts. Particular areas of …

… Biology is currently experiencing a revolution brought on by rapid developments in genomics and other … The research efforts of the group have concentrated in demonstrating the power of data … Science  356: 82-85 Ovchinnikov S. et al. (2017) Protein structure determination using metagenome sequence data. …

… Yeah. DAN: Yeah. So that involves figuring out the structure of that pure molecule. And that can that can take … DNA sequencing and actually get to the DNA sequence – sequences for the genes that code for the proteins that produce secondary metabolites. Do you …

… attraction to natural products was dual, the beauty of the structures and also the challenge and thinking about making … do engineering to improve the physical properties of a protein and make it easier to work with. But sometimes, what … And so there are different ways that we decided which sequences made it onto that list. So the majority of them …

… The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis … The Microbial Program focuses on using advanced sequencing technologies to explore … and single cells. This effort uncovers novel genes, protein families, and pathways, enhancing our understanding …

… Overview The JGI provides sequencing, synthesis, and targeted metabolomics support for DOE-BER funded awards, including awards … The JGI is inviting researchers using the U.S. Culture Collection Network (USCCN) to nominate their strains for sequencing, … The JGI performs sequencing, metabolomics and synthesis on behalf of the …

… families known up until now, and identified many novel structure predictions,” said lead author on the paper … (IMG/M) database, they successfully crafted the Novel Metagenome Protein Families (NMPF) Catalog.  “We can now … the process hinges on referencing to existing genome sequences.  Some of these proteins are what the scientists …