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… DAN: You’re listening to the US. .Department of Energy Joint Genome … at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … is, is directly that in the face of growing antibiotic resistance, so we’re looking in soil that’s extremely …

… collaborative user projects, the JGI’s Plant Program delves into the natural world’s potential to address global challenges by exploring plants’ role in capturing carbon, detoxifying soils, interacting with … into chemical energy — and its implications for carbon sequestration, renewable energy and agricultural …

… Hey, Alison Takemura: Hey, Dan. Dan Udwary: Today we’re going to talk to Kate Duncan. And Kate is– I should ask, you … before– or kind of around about when the first genome sequencing was done. But natural products– marine natural … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the …

… live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have … is nowadays, but traditionally, somewhere in the neighborhood of 60 to 70% of all of the medicines that we use are … Was it because were you already experiencing antibiotic resistance at that point?  DAN: Yeah, I’m glad you asked. …

… of Natural Prodcast. A little bit of a bonus episode, since I’m off schedule, but this is an important one that … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a … in natural products, this is just pretty amazing with spearheading this endeavor at JGI. So SMC is a new platform …

… back to a new session of Natural Prodcast. I’ve got two things I wanted to tell you about in this introduction. First … which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … to the genome mining-based approaches are that other than resistance genes, you have no way of knowing of whether or …

… Innovative technology from this biomanufacturing collaboration is available for licensing. The Science … HAp granules.  The JGI team demonstrated that the osteoyeasts can produce a gram of hydroxyapatite per kilogram of … The work conducted by the U.S. Department of Energy (DOE) Joint Genome Institute ( https://ror.org/04xm1d337 ), a DOE …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the … our own applications. Nowadays, we talk about antibiotic resistance, and I was talking to my daughters– what did they …

… view of plant evolution and adaptation.    Understanding how genes are regulated is like deciphering the complex … are activated to sustain life’s processes.  Traditionally, mapping this intricate network of regulatory “switches” in … Now, with improvements to DNA Affinity Purification Sequencing (DAP-seq), these barriers are falling. As  …

… UDWARY: It’s been a while, but Natural Prodcast is back again for another round of episodes. If you stick around for … Science program. It used to actually stand for Community Sequencing Program. Also CSP, same acronym. But as JGI, as a … facility, evolved, and as we started to do more than just sequencing, we thought the name community sequencing program …

… studying regulatory mechanisms of, first, E. coli and then Rhodobacter spheroides . And that got me really interested … active against Sartoria which is a really big pathogen of wheat in cereal crops in Europe. And the molecule is derived … NIGEL MOUNCEY: Oh, sure. I think our legacy obviously is in sequencing.  DAN: Of course.  NIGEL MOUNCEY: Sequencing the …