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… of Natural Prodcast. This week, Alison and I talk to Roger Linington, from Simon Fraser University in British Columbia, … program, which stands for International Cooperative Biodiversity Groups, and it’s this great program funded by the … understand the chemical diversity and chemical utility that nature has to offer us. I found this conversation really …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … Natural Products conference, which took place last January 2020 in San Diego. San Diego, of course, is the “home turf” … of those, you know, early-on reactions that we see. And so nature does that as well. But it does it with exquisite …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … recommend David Hopwood’s book called  “Streptomyces in Nature and Medicine.” It’s obviously focused more on the … to be here and be able to discuss this incredible, natural diversity that we have at our fingertips. So I’m very …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all … see. So it doesn’t seem to be a correlation between biodiversity in taxa and biodiversity in secondary metabolites. …

… is Professor Cassandra Quave from Emory University, with joint appointments in the School of Medicine and College of … I’m talking about is called the Convention on Biological Diversity . And there’s something called the Nagoya Protocol … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … I have been in – working in secondary metabolism for almost 20 years now. Which when I did the math, that was a surprise … how funny, you know, the human endeavor of understanding nature is: we want to categorize things into these arbitrary …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … But um, yeah, so secondary metabolism is throughout nature, except maybe for animals and humans, not as much. … derivatives of natural products.  ALISON: Like such a large diversity can have similar effects, I think is also really …

… … DAN: You’re listening to the US. .Department of Energy Joint Genome … we have no idea what natural products are doing in nature. And it’s a really difficult thing to unpack … similar to like human crops like corn. There’s low genetic diversity in the crop. So they’re susceptible to disease. …

… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s … and domains, to identify enzyme coding genes that are signatures for the presence of a specific type of biosynthetic … you to get a bird’s-eye perspective on the biosynthetic diversity element of these genomes. And you see how they’re– …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about … we discussed in the primer podcasts ( part 1 here , part 2 here , and part 3 here ), which you should be able to find …

… for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took a little break, but I’m hoping that from … A few examples of those are obviously expanding the diversity of known secondary metabolites and their … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

… of natural products, Professor Bill Fenical from Scripps Institution of Oceanography in San Diego. Bill is a pioneer … seems hard to believe in retrospect. BILL FENICAL: Well, in 2021, absolutely hard to believe. But when you go way back, … it took 15 to 18 years before we were able to convince the diversity of marine ecologists that they needed to consider …