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… by bacterial or fungal metabolism by microbes, will have a functional role. We started from that. Evolution doesn’t … features of the compound. For example, lipids– doesn’t matter if it has one extra carbon or two or one less, at the … move a little bit away from that to try to unmask chemical dark matter. And the idea behind this is that, if we …

… solutions.  The program has been a pioneering effort in functional genomics since 2012, with a focus on addressing critical energy and environmental challenges. Through innovative research in synthetic biology, the … The DNA Synthesis Program plays a central role in advancing functional genomics, focusing on developing genetic systems …

… to as “data” for the remainder of this policy) produced through all user projects accepted FY22 and later through the Community Science Program (CSP), Facilities … PIs or co-PIs) who wish to include use-restricted data in publications, or who wish to redistribute data in any way …

… Paul Jensen and Bill Fenical. And we connected to JGI through the Community Sequencing Program, and they worked … then the organisms all around us or the, you know, the bio matter that’s around us now? Brad: Yeah, I mean, petroleum … an impact, like the domoic acid story, and be able to have global science-type connections, and be able to use our …

… the quality of single-cell genomes and directly link functional information with individual cells. Research Team  … offers the first quantitative Stable Isotope Probing (SIP) Metagenomics pipeline that utilizes internal analytical … measure environmental microbiome activity levels.This functional assay lets us move beyond cataloging the genes of …

… delves into the natural world’s potential to address global challenges by exploring plants’ role in capturing … and protein folding models, to improve the accuracy of functional predictions and speed up genome analysis. … Plant Flagship Genomes are selected through discussion with the JGI Plant Genome Advisory …

… samples — including microbes, fungi, plants and soils. Through a combination of experimental workflows and … with gene expression, providing deeper insights into functional genomics. A key focus is understanding the … designed to demystify the complexity of dissolved organic matter (DOM) across a variety of environments. ENVnet allows …

… and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … know nothing about biology. Biology hates us. It’s a little dark, but. [laughs] DAN UDWARY: Yep. ALISON TAKEMURA: It’s … can be applied to secondary metabolism almost always, no matter what that is. Almost always. How do people do that? I …

… started during my PhD. And then I actually found out, through a connection of my supervisor, that in parallel, … we actually add features as they come, and this is done through also a process where you say, OK, I want to build … grad student with Michael. And we did it together. Did the global analysis of biosynthetic gene clusters across, well, …

… Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, … And at the time, we didn’t have a genome. So we had to go through different ways. It wasn’t a time where you would … the evolution of secondary metabolite pathways as viewed through metagenome studies, and what more JGI and others can …

… AI-ready data and professional expertise to support the global research community in studies of complex biological … systems. We optimize our service to the community through responsibly managing our people and resources. Our … in resource resilience and economic growth. The DOE, through its BER program, plays a central role in advancing …

… the scientific community at large with access to high-throughput sequencing, synthesis, and metabolomics at the … call is for PIs who have never led a JGI project, and the Functional Genomics call is for projects that translate … into biological function. The  New Investigator and Functional Genomics calls do not require an LOI.  Projects …