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Sequencing Technologies & Products
… well-integrated across JGI departments to ensure a robust offering of sequencing capabilities and products to our users. This … advanced sample management (quality assurance/quality control [QA/QC]), large-scale liquid handling automation, … An assay used for profiling transcription factor binding sites across entire …
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Metabolomics Program
… The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to enhance our understanding of genome science, organisms, and ecosystems at the … Integrating genomics with metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables …
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Natural Prodcast Episode 8: Eric Schmidt
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … The other way – the RiPP way, is to make a protein using the normal cellular way of making proteins, with a … reactions are timed are really going to tell us how to control some aspects of chemistry with the enzymes and so …
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Institutional User Agreements
… — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing data for synthesis. This agreement, required … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is …
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FICUS
… for researchers to request the capabilities and expertise of multiple DOE National User Facilities in one research … Successful applications will focus on high-risk/high-payoff proposals within the focused topic areas that can be … provides customized analysis, the JGI also participates in publication of results. …
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Natural Prodcast Episode 14: Nigel Mouncey
… DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took … NIGEL MOUNCEY: Well, we hope that all of the vaccines and controls that are in place will help us get on top of this … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …
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Natural Prodcast Episode 16: Marcy Balunas
… know that that’s ever necessarily like a good description of anyone because chemistry means a lot, especially when … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … to integrate with the metabolomics data. So we’ve got a control and a treatment for example and we get LCMS data for …
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Biodesign
… dedicated to user project design, assembly, and quality control Strain Engineering Group : a research & development … automations for DNA design, assembly and analysis Overview of biodesign products The JGI Biodesign platform enables … BOOST provides a suite of tools to automate sequence design for assembly by Gibson, …
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Tuning of Gene Expression in Clostridium phytofermentans Using Synthetic Promoters and CRISPRi
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Microbial Program
… The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … associated with microeukaryotes, enhances our understanding of terrestrial biogeochemical cycling and inter-organismal …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… more than 10 papers, including two Nature Plants publications, in five years, have come out of the … soup permits researchers to quickly test different ways of controlling the pathway enzymes, and thus evaluate changes … called CRISPR inhibition or CRISPRi, works (see the article Transcriptional control of  Clostridium autoethanogenum …
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Single Cell Research Group
… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such effort is targeted at environmental … gap is also reflected in the strongly biased representation of sequenced genomes in the public domain, the bulk of which …
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