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… bit more into fungi and learning the differences of all the genetic differences and then expanded on on that knowledge … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever … are active in doing this kind of science and give them some recognition. I think that’s really important, especially for …

… the capabilities across at least two of the facilities, and generate datasets beyond what each of these facilities could generate by itself.   Accepted projects must address or be … provides customized analysis, the JGI also participates in publication of results. …

… critical requirements for amplifying the JGI’s impact. Data generated from a single investment will be reused for … two-factor authentication enabled to log in. Check our Help Site for additional information, including a Login … host taxonomy, conjugation potential, antibiotic resistance genes, and ecosystem information. …

… include exploration of the global diversity of alternative genetic codes (Science 2014), unearthing hundreds of … Science 2017, Nature Microbiology 2018), discovery of new genes with important biotechnological applications (e.g., … Camargo AP. et al. (2023) Identification of mobile genetic elements with geNomad. Nat Biotechnol . Epub. Neri …

… and BiG-SLiCE, and now the BiG-FAM database of biosynthetic gene cluster families. And he tells us about forthcoming … to my submission, they were saying that natural product identification– biosynthetic gene cluster identification was … the very small precursor peptides that end up being post-translationally modified into ribosomally synthesized …

… always find at naturalprodcast.com or through the JGI website at jgi.doe.gov . There’s a lot more to talk about … It was unpublished at that point. But people would push out gene clusters maybe once a month at most. Maybe twice a … And it’s more basic science. And it’s less focused on translation. But we plug– we want to plug these organisms …

… complexity, and encode for a treasure trove full of novel genes ready to be tapped for downstream applications. … threats in environmental samples. This work combines third generation sequencing and machine learning to enable fast, accurate identification. … A complete publication list available at Google Scholar. Dutkiewicz, Z. …

… on large-scale sequencing efforts that survey the vast phylogenetic and ecological diversity of fungi and algae, … and engineered strains. This approach allows for the identification of key functional traits that have direct … members of microbial communities, cataloging gene markers, and producing environmental genomes to support …

… America brought to the UK? ROGER:  Yeah, it’s difficult to generalize, of course, but I felt overall that the British … this new SMART technology from UCSD, which is doing pattern recognition in comparing spectras to one another. And … published and then curate and enter those which are not deposited. DAN:  Invaluable resource.  ROGER:  It’s an amazing …

… a term that is not useful, then I think it needs to be revisited. And I think that a secondary metabolism as a field, … the active site of an enzyme. So there is no promiscuity, generally speaking, in primary metabolism. Nevertheless, … antibiotic is really an antibiotic in nature, what is the general belief is that that is the case when there is a …

… We're trying to. JACKIE: So I was reading on your website that-- speaking of hormones, that you're also using … oftentimes will bind to receptors within biosynthetic gene clusters. Specifically, these are Tet repressors that oftentimes turn off these biosynthetic gene clusters. And so we've been really interested in trying …