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… metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables exploration of energy … JGI scientists are able to link metabolic activity with gene expression, providing deeper insights into functional … a web-based service returns a list of scored reaction and gene matches associated with metabolites and a list of …

… bit more into fungi and learning the differences of all the genetic differences and then expanded on on that knowledge … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever … are active in doing this kind of science and give them some recognition. I think that’s really important, especially for …

… including BBTools ? Click to find that on our archive site.  …

… the capabilities across at least two of the facilities, and generate datasets beyond what each of these facilities could … provides customized analysis, the JGI also participates in publication of results. … Proposals for the annual FICUS … introduces the NEON resource, a network of field research sites designed to collect long-term open access ecological …

… and BiG-SLiCE, and now the BiG-FAM database of biosynthetic gene cluster families. And he tells us about forthcoming … to my submission, they were saying that natural product identification– biosynthetic gene cluster identification was … the very small precursor peptides that end up being post-translationally modified into ribosomally synthesized …

… always find at naturalprodcast.com or through the JGI website at jgi.doe.gov . There’s a lot more to talk about … It was unpublished at that point. But people would push out gene clusters maybe once a month at most. Maybe twice a … And it’s more basic science. And it’s less focused on translation. But we plug– we want to plug these organisms …

… include exploration of the global diversity of alternative genetic codes (Science 2014), unearthing hundreds of … al. (2017) Giant viruses with an expanded complement of translation system components.  Science  356: 82-85 … Science 344(6186):909-13 … Research Efforts … Selected Publications … For further details, please reach out to the …

… on large-scale sequencing efforts that survey the vast phylogenetic and ecological diversity of fungi and algae, … and engineered strains. This approach allows for the identification of key functional traits that have direct … members of microbial communities, cataloging gene markers, and producing environmental genomes to support …

We're trying to. JACKIE: So I was reading on your website that-- speaking of hormones, that you're also using … oftentimes will bind to receptors within biosynthetic gene clusters. Specifically, these are Tet repressors that oftentimes turn off these biosynthetic gene clusters. And so we've been really interested in trying …

… a term that is not useful, then I think it needs to be revisited. And I think that a secondary metabolism as a field, … the active site of an enzyme. So there is no promiscuity, generally speaking, in primary metabolism. Nevertheless, … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

America brought to the UK? ROGER:  Yeah, it’s difficult to generalize, of course, but I felt overall that the British … this new SMART technology from UCSD, which is doing pattern recognition in comparing spectras to one another. And … published and then curate and enter those which are not deposited. DAN:  Invaluable resource.  ROGER:  It’s an amazing …

… are at the core of many environmental processes, and the genetic makeup of microbial species and communities forms …