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Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … did it all begin? DAN UDWARY: Yeah, I love to hear people’s origin stories. ALISON NARAYAN: For me, the initial … that it’s like always the same. So I would say we run enzymatic reactions anywhere from 4 degrees to room …

Mass spectrometry based metabolomics Below is a table of standard product offerings, including a description of … the product and deliverables as well as target cycle times from sample receipt to completion of standard analysis.  Raw … is sequenced Combined assembly of related fractions originating from the same sample, annotation ( IMG/M ), …

… … DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m working on this the … did you get started. I know you’re not classically trained originally in natural products. And so do you want to give … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

… for researchers to request the capabilities and expertise of multiple DOE National User Facilities in one research … provides customized analysis, the JGI also participates in publication of results. … Proposals for the annual FICUS call with EMSL begin with a Letter of Intent (LOI) from a researcher, briefly describing the project …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … This time, we’ve got a great interview with Ben Shen, from the Scripps Research Institute in Jupiter Florida. This … traditional limitation for natural products –  say if we originated, say, taxol, for example. If you say isolate …

… — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is … and delays on the work. The transfer of a proposal from one commercial institution to a new commercial …

The IMG group owns and maintains integral components of JGI’s production workflow, and is responsible for the … data and serving them to users via the Integrated Microbial Genomes & Microbiomes (IMG/M) system. Research Team    … The … species specificity of single cells and genomes extracted from metagenomes, and also as a metric for quality control …

… analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … catalog : Beyond minimal draft and improved draft microbial genomes the program offers single-cell sequencing, … of sequence space:  The JGI generates reference genomes from diverse bacterial and archaeal lineages to improve …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great … mining software we mentioned: “ EvoMining reveals the origin and fate of natural product biosynthetic enzymes. ” …

… as user facility that aims to provide access to state-of-the-art DNA synthesis and assembly technologies to the … on developing methods for converting digital information from sequence databases into biotechnological or … applications.  We are interested in:  characterizing novel enzymatic activities using phylogenomic driven approaches, …

… approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … Microbiology , 15032. 10.1038/nmicrobiol.2015.32 … Selected Publications … For further details, please reach out to the …

… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … we get to present our conversation with Marnix Medema , from Wageningen University in the Netherlands. Marnix is … are protecting the plants against pathogens. So usually fungal or oomycete pathogens. In this case they worked on a …