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… and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … regions of secondary metabolism should be. That’s still largely homology based, but then you’re using kind of a … might be everywhere, but only at a certain kind of coarse scale. DAN UDWARY: Yeah I think that’s right. That’s why I …

… as user facility that aims to provide access to state-of-the-art DNA synthesis and assembly technologies to the … mining and sequence design with scaling the production of large, difficult to synthesize constructs such as those … engineering pathways to function in heterologous hosts, by combining combinatorial synthesis, high-throughput …

… well-integrated across JGI departments to ensure a robust offering of sequencing capabilities and products to our …   Overview of sequencing products The JGI operates highly scaled short- and long-read sequencing pipelines. This … management (quality assurance/quality control [QA/QC]), large-scale liquid handling automation, and sequence …

… Science Program (CSP) provides the scientific community at large with access to high-throughput sequencing, synthesis, and metabolomics at the JGI for projects of relevance to Department of Energy (DOE)  Mission Areas . … Three calls fall under the umbrella of our CSP: The Large Scale call is for expansive projects that leverage a range …

… DAN: You’re listening to the US. .Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … in those two fields and the ability to process samples at scale. So, lots of samples. ALISON: Yeah, how many samples … you for that insight. DAN: So I suppose, coming up with large collections of new microbes and new activities, feeds …

… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of … The “Great Plate-Count Anomaly” first described by Stanley and Konopa in 1985, which highlights our skewed understanding of microbial metabolism towards a minority of cultivated …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and associated viruses that all … in how plants self-organize, influence, and are influenced by microbial partners. We use a variety of genomics-powered …

… and analysis will be paid for by the Department of Energy’s funding of the JGI. There is no cost to the user and no granting of funds.    Proposal Call FICUS CSP Large Scale CSP New Investigator CSP Functional Genomics JGI-TMF …

… Undergraduate Research Experience (CURE) that consists of coordinated hands-on experiments across fungal biology … fungal species.  Students collect fungi, sterilize tissue, isolate genes and more. The metadata then goes into … Myco-Ed has:  ~50 lineages selected for sequencing 16 genomes released 20 members from 15 institutions 300+ …

… and rate and drive down the cost of producing riboflavin at scale.  DAN: Got it.  NIGEL MOUNCEY: And I did that for … worked for the best part of 20 years on products that were largely in commercialization, I thought it’d be great to … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

… The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to enhance our understanding of genome science, organisms, and ecosystems at the … exploration of energy and nutrient exchange, as well as microbial and plant responses to environmental changes. With …