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… DAN: Hey, everybody. Welcome back for another episode of … we were mentioning before, of more complex secondary metabolites that an organism might want to use to affect its … these quorum sensing systems which again would just in many cases be these two genes for a synthase and a transcription …

… DAN UDWARY: You’re listening to the Department of Energy … do you see genome mining and looking for secondary metabolites in the genome as relevant to the JGI mission? DAN … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, …

… DAN UDWARY: Hey everyone and welcome back to a new session of … it can be looking for drugs from marine organisms, in which case you get to go to exotic tropical locations and go … of what we’re doing with the JGI with the Secondary Metabolites Collaboratory and trying to have a good catalog of …

… Every approved proposal starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or the submission of … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is …

… The JGI’s Metabolomics Program works to uncover the roles of small … with metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables exploration of energy and nutrient exchange, as well as microbial and … is focused on understanding the critical roles of metabolites in living systems, particularly as they relate to DOE …

… DAN: Welcome back for episode 9 of Natural Prodcast. This … know what we know. The information is scattered throughout literature. It’s across a huge array of different dates, … the gene cluster. Not to the discrete compound, in many cases.  DAN:  In many cases. Sometimes you can. ROGER:  …

… DAN UDWARY: Hey, everyone. I’ve got a great episode for you … microbial fermentation in huge quantities, 50,000 liter fermenters, to produce a kilogram of a drug, for … that should be is a microbiological puzzle, but it’s the case. This was one of the first ones that we worked on, …

… One of the JGI’s key assets is our user community, … have yielded numerous, high-quality outputs, such as data, publications and software. The JGI supports the entire data … Each portal lists a contact, or you can reach out via the form on our website.   … Looking for BBTools? Find it here.  …

… With collaborative user projects, the JGI’s Plant Program delves into … challenges by exploring plants’ role in capturing carbon, detoxifying soils, interacting with other organisms, and … resilience. The program’s discoveries support a plant based bioeconomy where plants are a major source of chemical …

… DAN UDWARY: You’re listening to the Department of Energy … Big picture, I want to understand how secondary metabolites evolve– who makes them, how do they spread, why do … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all …

… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic … material of uncultivated taxa of interest. One such effort is targeted at environmental cells that are from … Phylogenetic diversity estimates show that the gap between cultivated and uncultivated …

… The Mycological Curriculum for Education and Discovery  (Myco-Ed) is a Course-Based Undergraduate Research Experience (CURE) that consists … Beyond providing a scalable solution for production of … The Mycocosm portal supports the annotation, comparative analysis, and …