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… however they do so under strong constraints exerted by viruses. Research in the viral genomics group aims at … mechanisms involved in virus:host interaction and host cell take-over by viruses, and attempts to evaluate … abundant ocean viruses.  Nature . 537:689-93. … Selected Publications … For further information contact the Group …

… computed for nearly 28,000 bacterial and archaeal genomes. By clustering genomes based on their pairwise AF and ANI … ANI is used to ascertain the species specificity of single cells and genomes extracted from metagenomes, and also as a …

… introduction in natural products, so I might just start out by asking you know how did you get started. I know you’re … really fun that you want to– a new area of your lab is exploring? AARON PURI: Yeah. Thanks. So– DAN: Almost like … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

… in how plants self-organize, influence, and are influenced by microbial partners. We use a variety of genomics-powered tools to study this complexity, including single-cell and spatial transcriptomics barcode-based … of plant/environmental responses … Selected Publications … Research Team Alumni … For further details, …

… percentile*) DNA Synthesis Constructs <5kb in size Single gene or multiple small genes assembled to less than … Assembly, annotation ( IMG/M ), mapping 273/273 Metagenome Cell Enrichments Obtained by physical separation of a biologically relevant unit from …

… can just mediate so many kinds of interactions. And by understanding them, we can promote the health and … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … streams. This will all become clearer as we get into the genomics. So– ALISON TAKEMURA: I’m just enjoying the ride …

… people all over the word who have a common interest, united by natural products, DAN: You guys have put together a … is always associated with toxicity, basically, killing cells. ALISON: Right, because they’re so reactive. BEN: … DAN: Yeah, I don’t think your lab is gonna tackle that single handedly, right? So, yeah, getting the community …

Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire … program supports cutting-edge research in synthetic biology by synthesizing genes, pathways, and whole chromosomes for … The JGI's DNA Synthesis Science Group supports researchers exploring how to convert sequence into functional …

… usage. And I was recently challenged on that on Twitter by Francisco Barona-Gomez. And so he is here to, at least, … for example, in terms of the stereochemistry, such that single changes can lead to a particular high activity … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… communities and ecosystem function.  The Environmental Genomics group also hosts the Viral Genomics group . Research Team    … Nayfach S et al.  A … Microbiology , 15032. 10.1038/nmicrobiol.2015.32 … Selected Publications … For further details, please reach out to the …

… including a downloadable pdf of products categorized by Science Program.  … The majority of JGI projects come … required documentation here .  … You can request a JGI Single Sign On account at https://signon.jgi.doe.gov . This … for individuals associated with your proposal. Find our Publications Policy on our Data Policy & Support page.    … …

DAN UDWARY: So Alison, I’m really excited today. We have, by far, I think, one of the most decorated and legendary … we want a chemist to study the ocean. And I didn’t find a single job advertisement. But one day, I decided to really … natural products, his experiences in drug discovery, and exploring marine bacteria for novel chemistry. Related …