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… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … Yeah, bacteria sound like a good place, to me, to look for diversity because there are so many bacteria, because it is …

… Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … you to get a bird’s-eye perspective on the biosynthetic diversity element of these genomes. And you see how they’re– … we, for example, are really interested in metagenomes and microbiomes and figuring out which gene clusters are …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all … see. So it doesn’t seem to be a correlation between biodiversity in taxa and biodiversity in secondary metabolites. …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a … terms of the definitions, such that everybody could have a understanding of what we’re talking about. And while … is that you could, therefore, expect a lot of chemical diversity. So many compounds will fulfill the same function. …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … rich and underappreciated. And we’ve worked both with the microbiome. So, with symbiotic bacteria that live in animals … with animal metabolism itself, and it’s really amazing what diversity there is in animals. I think, even despite the …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … my Peace Corps volunteer stint, and that it was in all the maize. So the main food that you ate was called Papa, which … they deserve. They are so exciting. I get frustrated. Like microbiomes  – you know how that’s a big deal now. You go to …

… Plants are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and … genetics (RB-TnSeq), and computational genomics to better understand the plant-associated terrestrial world. Research … fungi, viruses. Resident viruses can be found in a myriad of bacterial strains, whereby they can modulate host …

… research is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and … to identify new divergent lineages and expand the Tree of Life. We then investigate the coding potential to find novel functions that may impact microbiome structure and biogeochemical cycles. Research …

… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such effort is … by Stanley and Konopa in 1985, which highlights our skewed understanding of microbial metabolism towards a minority of …

… to more easily integrate the expertise and capabilities of multiple Department of Energy Office of Science National … aims to encourage innovative research exploiting a diversity of capabilities. Previously, researchers had to … provides customized analysis, the JGI also participates in publication of results. …

… DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m working on this the … these, and Aaron and JGI are working together to try to understand the enzymology of their synthases so that we can … the answer would be that there’s actually a great deal of diversity within these methanotrophs for example, that are …