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… so I hope somebody’s going to find them useful! DAN: Among many other things, Ben is maybe best known as an … a class of natural product with a really cool chemical structure. We try to explain it, but it’s chemistry, so I … well. One is to do DNA sequencing. So upon sequencing many genomes, now we don’t have to, as in the past, go randomly …

… MARCY: And that they’re laid – unlike octopus which tend to their eggs and so they don’t get biofilm. Squid just deposit … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … almost never Actinomycetes. And so when we look at their genomes we don’t get the same kind of information that we …

… I would say are are still fairly unexplored in terms of their natural products chemistry, and he has a project with … And it actually was jumping onto the I ntegrated Microbial Genomes and Metagenomes, the IMG platform that JGI has that … “tail of the acyl homoserine lactone” can have different structures, and that is akin to what you’re referring to …

… So, I’ve always known Roger as an expert in natural product structure elucidation, but more recently, he’s been leading … Atlas , or NPAtlas, a freely accessible natural products structure database, which is going to be just invaluable to … is a central repository, which has all the structures and their corresponding gene clusters, and their MS and MS-MS …

… So he could see really into this– so he could look into the structure, really seeing that. And I’m always just looking … yes, sure, right. And yeah, so we worked on the Salinospora genomes. That was a really fun project. We had Brad on and … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all …

… provides customized analysis, the JGI also participates in publication of results. …

… Francisco Barona-Goméz, or Paco, as he prefers to be known among friends in natural products. He’s from Langebio in … that you need to do these coordination bonds, then many structures will be able to work. So, for example, in that … it is more related to what JGI does, which is sequence genomes. And we just published last year in the Nature …

… cluster database, and a tool for predicting natural product structures from genomes. And I was writing grants furiously to try to get … we also do a lot of the analysis. So we actually like to be among the first people to use these tools as well on … with AntiSMASH , which is available for analysis of your genomes on the web , or you can download a docker container …

… explores the vast diversity of fungi and algae to unlock their potential for bioenergy, environmental sustainability, … and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates the … and biogeochemistry. This research helps translate their genomic potential into practical applications, …

… 2014), unearthing hundreds of thousands of new viral genomes and their predicted hosts (Nature 2016, Science 2017, Nature Microbiology 2018), … the quality and completeness of metagenome-assembled viral genomes. Nature Biotechnol . 39(5):578-585. Nayfach S, et …

… for uncultivated microorganisms, by sequencing large populations of bacteria and archaea in their natural environments using single cell approaches. … catalog : Beyond minimal draft and improved draft microbial genomes the program offers single-cell sequencing, …

… organisms we’re finding– at least by looking at their full genomes — are really not like anything that’s been … Everything that we’re finding seems to be a new structure, and the microorganisms are novel. I mean, we have … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever …