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Developed in 2017, the PDT was established in part to help better-connect industry to … Office to facilitate these new interactions.  The PDT enables industry engagement through three primary routes:  … … enable research jointly sponsored by the Berkeley Lab and one or more partners for shared benefit. Industry partners …

… is being this engineer that’s constantly refining its designs. But sometimes if you’re looking at it from a zoomed … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all that stuff. And …

… be the amino acid that is relevant for the synthesis of proteins, and will more often end up in the active site of … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great … large-scale comparisons of biosynthetic gene clusters: “ A computational framework to explore large-scale biosynthetic …

The Metagenome Program uses advanced sequencing technologies to … and their metabolic functional potential. This research enables us to better understand how microbial communities … and their evolution. The Program focuses on developing computational tools and visualization resources that support …

… growth of DNA sequencing data, coupled with recent computational technology advances in management, processing … Science  356: 82-85 Ovchinnikov S. et al. (2017) Protein structure determination using metagenome sequence … Science 344(6186):909-13 … Research Efforts … Selected Publications … For further details, please reach out to the …

… … Dan Udwary: You’re listening to the Department of Energy … the project was a mixture, initially, of experimental and computational work. And that it involves some of these crazy … with sequence similarity, either we just looked at which protein domains are in a gene cluster or we did sequence …

DAN UDWARY: You’re listening to the Department of Energy … itself medicine, but the coding within the DNA codes for proteins that do the chemistry that put molecules together … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, …

The Fungal & Algal Program explores the vast diversity of fungi and … that enable fungi and algae to play a vital role in carbon cycling, biodegradation and biogeochemistry. This … analysis tools for comparative genomics of fungi. Mycocosm enables users to navigate across sequenced fungal genomes, …

The Facilities Integrating Collaborations for User Science … not only simplifies and streamlines this process, but enables scientists to conduct fundamental science … provides customized analysis, the JGI also participates in publication of results. … All proposals undergo technical …

… bind similar ligands. And so one of-- DAN: OK. The similar proteins are going to bind similar molecules. Yeah, OK. … actually produced. And once we figure that out, we have designed GFP based plasmids where we can actually then put … Cyclic Peptides Synthesis of Gamma-Butyrolactone Hormones Enables Understanding of Natural Product Induction Betsy's …

The JGI has diverse capabilities in: DNA and RNA sequencing, Sample … requests not on this list, or to discuss experimental design for a proposal, we encourage you to contact the … Metabolite annotation based on chemical standards or computational approaches. Relative abundance of identified …