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… and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … often the things that suffer first when it comes to genome assembly. Some of the common biosynthetic systems – like a … might be everywhere, but only at a certain kind of coarse scale. DAN UDWARY: Yeah I think that’s right. That’s why I …

The IMG group owns and maintains integral components of JGI’s production workflow, … the deployment of computational workflows at peta- and exa- scales on multicore and many core architectures with the …

And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … so they end up probably over time dispersing across the chromosome. So I think that’s my feeling.  And so it could … is what those would be. The work that we do at larger scale in order to look at the chemistry a little bit more …

… lab is divided into a DNA synthesis production group and a synthetic biology applications group. The DNA synthesis and assembly group: Our production group operates as user … interested in:  characterizing novel enzymatic activities using phylogenomic driven approaches, and understanding the …

Overview The JGI provides sequencing, synthesis, and targeted metabolomics support for DOE-BER funded awards, … generally conform to the guidelines for our  CSP Large Scale call .  Process Proposals may be submitted at any … for user proposals . … The JGI is inviting researchers using the U.S. Culture Collection Network (USCCN) to …

… know what they’re looking at, and hard to do on a large scale. And so– Marnix Medema: But in the end, I do feel that … pathway even if the genes are scrambled or altered in the chromosome. And so it becomes very difficult then to compare … clusters. And then they sequenced a really nice and good assembly. They were able to assemble a really high quality …

Institute provides advanced genomic capabilities, large-scale data and professional expertise to support the global … be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, in the journal Nature . Following … critical minerals and materials. Understand the assembly, function, and the behavior of microbiomes and …

… strengthens -omics technologies at the JGI by identifying the actual molecules present in an environment that influence system behavior.  Through this … profiles from diverse biological and environmental samples using advanced liquid chromatography mass spectrometry …

Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to enhance our understanding of genome science, organisms, and … in your custom Python applications but highly recommend using the workflow in  GNPS2 .   … In support of user …

I could see myself going in the future. So, then we were using these probes to look at host pathogen interactions … has been fun because then we’ve been able to blow out the scale a little bit for the project. DAN: Do you see broader … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

… approved proposal starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is …

… … DAN UDWARY: Hey everyone. Welcome back to Natural Prodcast. … work as exploring and exploiting biocatalysts – that is, using enzymes to do chemical reactions. Obviously, in my … Sure. ALISON NARAYAN: And so we usually start on small scale in the lab. So we’ll run things in like little …