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… do natural products based drug discovery, predominantly in diseases of importance to each host country. It was built … chemical ecology, from drug discovery in every possible disease target area, using an enormous array of different … benefit. But that’s not necessarily relevant to many of the diseases that we seek to treat. So, it may be that molecules …
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… to the genome mining-based approaches are that other than resistance genes, you have no way of knowing of whether or … isolating is going to be active. And even if you do have resistance genes, it may not be better than something that … You need more. You need other prioritization techniques, resistance genes or something. DAN UDWARY: Right. Right. …
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… that project. So they were studying this phenomenon called “disease suppression”, where the microbiome of a plant, so … it into another soil, and then you also have that same disease suppressive effect. But well, causal gene so that … take a sugar beet. Think about if a sugar beet might get disease, but then it’s microbes might help it. And so maybe …
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… strategy called RH-Seq can identify genes that promote heat resistance in the brewer’s/baker’s yeast Saccharomyces …
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… Was it because were you already experiencing antibiotic resistance at that point? DAN: Yeah, I’m glad you asked. … about the use of antibiotics is that eventually, antibiotic resistance is going to set in. The more you use an … that bacterium is going to evolve and develop some kind of resistance where it’s not affected by the antibiotic …
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