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… welcome, Nadine. ALISON TAKEMURA: What is the big picture for you in your lab? NADINE ZIEMERT: Big picture, I want to … I think. ALISON TAKEMURA: Oh! NADINE ZIEMERT: I needed a job during college or university, and I got this … having the same protocols– I think, still looking into standards– how do you say, standardization? DAN UDWARY: …

… so secondary metabolism is throughout nature, except maybe for animals and humans, not as much. You know, we have this … to protect those nutrients with antibiotics. They might need to secrete siderophores to pick up metals and bring … a little bit more giving. DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of …

Takemura, whose voice you’ll hear in a minute – we work for the US Department of Energy Joint Genome Institute, or … related to energy and the environment – problems that might need special technology for DNA sequencing, genomics, … the bark of the yew tree, is where it was originally discovered. And so that sounds great. There’s a natural source, …

… and the bacteria and how the chemistry is going back and forth between them is part of what fascinates me about what … with getting to something other than the sort of really standard kinds of things and natural products definitely … more bioactive – at least antimicrobials – bacteria that need more defenses, that want to defend the niche or …

Mexico, and an incredibly bright guy who’s been thinking for a long time about the evolution and natural products … So if you use a term that is not useful, then I think it needs to be revisited. And I think that a secondary … described it, I thought of primary metabolism as being the standard set of shared reactions that most living organisms …

It’s been a while, but Natural Prodcast is back again for another round of episodes. If you stick around for the … Science Program , or CSP, which is the main mechanism by which users work with our facility to do science. Since I … So we cannot work on health related projects. We really need to fit– a project needs to fit under this umbrella. Now …

I think it must’ve been about 2001, maybe, and so it was before smartphones and before laptops and everything. And I … the University that I was at that did just this. And I discovered it was called “marine natural products.” And that … And then, from an genomic point of view, I mean, I don’t need to say to you, but they’re unprecedented in the terms …

… … DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m … They just have this very restricted niche. And they do need broad host-range genetic tools so it’s more complicated … woods then. [LAUGHTER] JACKIE: So we’re kind of across — covered quite a few different topics. And so right now what …

… work and outline roles and responsibilities resulting in a formal Statement of Work (SOW). All work performed at the … users must first log in (Note: new users of the JGI will need to register and create a login at … your Project Manager will facilitate project execution by: Metadata verification and coordination with IMG , GOLD …

… of secondary metabolism.  DAN: Hello, and welcome back for Episode 7 of the Natural Prodcast. It’s been about a … without which, you know… If you asked me, Ben, you discovered -if can make something you have to have some … natural product could be biosynthesized, then you need to develop enabling technologies. ie how to translate …

Antarctic algae need their vitamins; zinc fuels some of their most important … other oceans. That zinc turns out to be extremely important for polar phytoplankton.  After peering into the function … CSP projects publicly available at the PhycoCosm portal . Byline: Menaka Wilhelm   … The U.S. Department of Energy …

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