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… wise maybe, what genome mining is, then, is looking at DNA sequence and trying to find the things that you want to … from certain kinds of environments or certain kinds of species or whatever. So for example, if you wanted to go … perspective, I would think that genes that are no longer needed would end up being purged from populations. …

… because – mainly it’s due to the emerging technology on DNA sequencing and synthetic biology. But also the … of nature as a scientist, nature is doing science, way longer than we as a civilization, supposedly.  DAN: By a few … Fleming – the discovery of penicillin from the fungal species – probably told us that fungi could be very …

They produce a large array of different molecular species related– chemically related– but nevertheless we did … that people are using in the clinics were kind of kidnapped from nature without paying attention to the … genome mining software we mentioned: “ EvoMining reveals the origin and fate of natural product biosynthetic …

Review JGI sample QC requirements and protocols Obtaining DNA and RNA of suitable quantity and quality has been the … project. It is imperative that users properly assess DNA or RNA mass prior to shipment to the  JGI. The documents … of Sample QC Sample Quality and Contamination JGI’s Genomic DNA Sample QC Protocol JGI’s Total RNA Sample QC Protocol …

… been doing a lot of this work. And we’ve isolated some rare actinomycetes from sediment cores in Antarctica that … chemistry has been around in natural products for a lot longer than genome sequencing, when we do a mass spec– a … to hear from you. We have projects in genome sequencing, DNA synthesis, transcriptomics, metabolomics, and natural …

… at the Broad that was looking to develop new methods for DNA sequencing of microbes. And what kept breaking our … to sequence is, you have to have a sequencer that can read longer than the repeat, otherwise, you have no idea how to … that could have something to do with it. We saw hints of a rare advantage. So if you’re not the most popular pathogen, …

… program, which stands for International Cooperative Biodiversity Groups, and it’s this great program funded by the … of biosynthetic gene clusters and biosynthetic gene cluster fragments, and all kinds of other crazy things. What do you … to hear from you! We have projects in genome sequencing, DNA synthesis, transcriptomics, metabolomics, and natural …

… are novel. I mean, we have Streptomyces , but they’re new species. And they have very similar [genomes] to other … or whatever you’d like, whatever D– you can submit any DNA sequence really, and it will go through SMC’s pipeline. … have just over a million BGC– or sorry, just over a million DNA sources. And so a “source” is some source of DNA. It …

… of that compared to some of the other guys that are no longer with us, like Dick Moore and Paul Scheuer, John … We now have cell pellets. And we’re pulling genomic DNA out of those cell pellets. So, we’re about ready to send … historical terms, has avoided looking at some of the most rare and non-obvious microbes. The pharmaceutical industry …

I talked about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, … of those 150 plus people. I have to admit, as a PI, I’m no longer impressed by that number. But as a postdoc, I … family would be a set of gene clusters across different species, which all encode the production of either the same …

… – problems that might need special technology for DNA sequencing, genomics, metabolomics, and synthetic … a molecular biology term. We recorded the Primer as a much longer conversation, which I cut into more digestable … at MIT, and I studied microbial ecology. I studied Vibrio species in the ocean, so heterotrophic bacteria. Now, we …

The Joint Genome Institute's DNA Synthesis Platform capabilities support researchers … tools for workflow management and novel automations for DNA design, assembly and analysis Overview of synthesis products The JGI DNA Synthesis platform enables users to validate hypotheses …