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… able to produce chemistry that deals with reactive oxygen species and so potentially could go down that route.  DAN: … local environments, and so they don’t transfer a lot of DNA back and forth, especially across species. And so then … And so we’ve been working with metals and in particular rare earth elements or Rare Earth metals with our cultures.  …

… the  product offerings and are unrestricted for use. … For DNA synthesis projects: data are subject to a  two-year … Inventory of Composable Elements (ICE) repository and/or DNASU Plasmid Repository) at the end of the embargo period. … two years after release to JGI portals). JGI will no longer produce use-restricted data except in already active …

… wise maybe, what genome mining is, then, is looking at DNA sequence and trying to find the things that you want to … from certain kinds of environments or certain kinds of species or whatever. So for example, if you wanted to go … perspective, I would think that genes that are no longer needed would end up being purged from populations. …

… program, which stands for International Cooperative Biodiversity Groups, and it’s this great program funded by the … of biosynthetic gene clusters and biosynthetic gene cluster fragments, and all kinds of other crazy things. What do you … to hear from you! We have projects in genome sequencing, DNA synthesis, transcriptomics, metabolomics, and natural …

… are novel. I mean, we have Streptomyces , but they’re new species. And they have very similar [genomes] to other … all of those have ended up in the SMC database. There’s a web front end for it, and it’s just a massive pile of data. … or whatever you’d like, whatever D– you can submit any DNA sequence really, and it will go through SMC’s pipeline. …

They produce a large array of different molecular species related– chemically related– but nevertheless we did … that people are using in the clinics were kind of kidnapped from nature without paying attention to the … genome mining software we mentioned: “ EvoMining reveals the origin and fate of natural product biosynthetic …

… because – mainly it’s due to the emerging technology on DNA sequencing and synthetic biology. But also the … of nature as a scientist, nature is doing science, way longer than we as a civilization, supposedly.  DAN: By a few … Fleming – the discovery of penicillin from the fungal species – probably told us that fungi could be very …

The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for … and environmental sustainability. Fungi, with million species, are essential for ecosystem functioning — … analysis and genomics data exploration. … The Mycocosm web portal provides data access, visualization, and analysis …

… been doing a lot of this work. And we’ve isolated some rare actinomycetes from sediment cores in Antarctica that … chemistry has been around in natural products for a lot longer than genome sequencing, when we do a mass spec– a … to hear from you. We have projects in genome sequencing, DNA synthesis, transcriptomics, metabolomics, and natural …

… at the Broad that was looking to develop new methods for DNA sequencing of microbes. And what kept breaking our … to sequence is, you have to have a sequencer that can read longer than the repeat, otherwise, you have no idea how to … that could have something to do with it. We saw hints of a rare advantage. So if you’re not the most popular pathogen, …

… – problems that might need special technology for DNA sequencing, genomics, metabolomics, and synthetic … a molecular biology term. We recorded the Primer as a much longer conversation, which I cut into more digestable … at MIT, and I studied microbial ecology. I studied Vibrio species in the ocean, so heterotrophic bacteria. Now, we …

… of that compared to some of the other guys that are no longer with us, like Dick Moore and Paul Scheuer, John … We now have cell pellets. And we’re pulling genomic DNA out of those cell pellets. So, we’re about ready to send … historical terms, has avoided looking at some of the most rare and non-obvious microbes. The pharmaceutical industry …