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… efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM database of biosynthetic gene cluster families. And he tells … being post-translationally modified into ribosomally synthesized peptide natural products. And they built a few of … of biosynthetic gene clusters. But with all of the other IMG kind of hooks into IMG’s data. IMG being Integrated …

… via the Genome Portal , at the following sites: Microbes: IMG (citation: https://doi.org/10.1093/nar/gkaa939 ) Metagenomes and Single Cells: IMG/M   (citation: https://doi.org/10.1093/nar/gkaa939 … functional annotation/curation of your genomes Microbial (IMG–ER) Metagenome and Single Cell (IMG/ M-ER) Fungal …

… the broader community.  We focus our efforts on integrating database mining and sequence design with scaling the production of large, difficult to synthesize constructs such as those involving biosynthetic … methods for converting digital information from sequence databases into biotechnological or environmental …

… S, et al. (2021) Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome. Nat Microbiol . … Science   355(6322):294-298 Paez-Espino D. et al. (2017) IMG/VR: a database of cultured and uncultured DNA Viruses and …

… biological insights from sequence data, employing IMG data and tools for comparative analysis, visualization … The Integrated Microbial Genomes & Microbiomes system ( IMG/M ) supports the annotation, comparative analysis, and … to enable comprehensive comparative analysis. Importantly, IMG/M provides data and tools via a graphical user …

… The IMG/M system serves as a community resource for comparative … three domains of life, in a uniquely integrated context. IMG/M provides tools for analyzing the functional capability … the context of reference isolate genomes included from the IMG/M system. … IMG/PR is a plasmid genome resource featuring the largest …

… of white. To researchers searching for sequences of RNA viruses in large data sets, their work may be akin to … from the JGI’s Integrated Microbial Genomes & Microbiomes (IMG/M) system. “We then looked into many more samples and … did the scope of the project.” To this end, Kyrpides emphasized, the contributions of the numerous JGI science users …

… them are actinobacteria. And so we get a lot of them from databases of organisms, so things like the NRL database - or … the promiscuity of one of the previously best studied SVR receptors. And so previously, a lot of these have been … can activate these, utilizing some of these already synthesized molecules. DAN: OK. These receptors are coming from …

… in the terms biosynthetic gene clusters and genome size. And they’re so complex. There’s so much still to … gene clusters of those.And they’re just like nothing in databases that currently exist. We looked at chemistry, so … something new? And we could only do this by comparing it to databases that were quite often commercial, that were quite …

… of Biosynthetic Clusters , which is a subsection of the IMG data portal , which is a larger portal for microbial … there that’s not JGI’s. It’s called MIBiG , which is the database that has the “minimum information about a … cluster makes a product and how a product should be synthesized based on its structure, that we should be able to tie …

… kinds of organisms, from plants and fungi to microbes and viruses. Listen in to explore the data that illuminates …