Search

Describing the largest analysis to date of the modified DNA base … on the largest analysis of 5mC distribution across the fungal tree of life to date, involving more than 500 species … that unlike most flowering plants and animals, fungi lack gene body methylation. The analysis revealed that 5mC in …

… bit more into fungi and learning the differences of all the genetic differences and then expanded on on that knowledge … not enough time and money. I mean, we have a huge marine fungal project in collaboration with Bill Fenical at … it was amazing. And now you have– just to the exponential expression of all these genomes and what can happen with all …

DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … ALISON TAKEMURA: I know that it’s looking in the genome for genetic elements of interest, you know, something like … it has a really interesting biosynthetic pathway because fungal genes are cool. And if you like fungal genes, you …

… for another episode of Natural Prodcast. Right now I’m working on this the afternoon of the day I’m due to release it, … and he has a project with the JGI to synthesize the genes for and explore the chemistry of quorum sensing … of these or any organisms. So developing good heterologous expression hosts like maybe in many fields now like in …

The focus of this group, in recent years, has been to bring generalizable … with little to no genetic tools enabling heterologous expression and functional exploration.  The developed …

… four forests, researchers have leveraged data from the 1000 Fungal Genomes project to form new connections between fungal guilds, genes and function. If a tree falls in the forest — whether … in four forest ecosystems, extracted RNA to understand gene expression, and developed new tools to map that soil RNA to …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … Yeah, so any metabolite, produced by bacterial or fungal metabolism by microbes, will have a functional role. … the active site of an enzyme. So there is no promiscuity, generally speaking, in primary metabolism. Nevertheless, …

… for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took a little break, but I’m hoping that from … my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for a couple … explore the regulation of biosynthetic gene cluster expression in organisms. And that’s led by Hiroshi Otani …

… oftentimes will bind to receptors within biosynthetic gene clusters. Specifically, these are Tet repressors that … that you can turn on the natural product, say clusters or expression systems so that-- BETSY PARKINSON: Exactly. DAN: … students, we obviously can't put any antibiotics or antifungals in there. So they get just a smattering. JACKIE: …

… to onboard users and guide them through the process of working with our facility. This includes help with: preparing a Statement of Work, … DNA Synthesis and Single-Cell Genomics Vivian Ng Fungal Genomics …

Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more nuanced …

Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, … fungi. Mycocosm enables users to navigate across sequenced fungal genomes, and to conduct comparative and …