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… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … Yeah, so any metabolite, produced by bacterial or fungal metabolism by microbes, will have a functional role. … will be very flexible. They will allow promiscuity and the enzymes are driving the production of these compounds, …

… Leveraging massive comparative genomics to decode millions of … fungi remain largely mysterious. Only about 200,000 fungal species have been named. Among those sequenced, … over a billion years of evolution offers catalogs of enzymes, secondary metabolites, and other parts lists for …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … episode is our conversation with Nancy Keller, a fantastic fungal natural products researcher from the University of … I wish we could predict. I wish we could look at these enzymes and predict, and really place it to structure. …

… to onboard users and guide them through the process of working with our facility. This includes help with: preparing a Statement of Work, completing a formal User Agreement, … Please review our FAQ in advance of contacting the PMO office.  … Before work can start on any approved proposal – including the submission of samples for sequencing, or the …

… The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, Biodesign and pathway engineering Mass spectrometry based metabolomics Below is a … to determine coverage of variants depends on project Fungal Minimal Draft Lower coverage short-read whole genome …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … where I was a graduate student. Aflatoxin, of course, is a fungal natural product which is a liver toxin when humans … way of making proteins, with a ribosome. Then, some other enzymes chop the protein into smaller pieces, and other …

… four forests, researchers have leveraged data from the 1000 Fungal Genomes project to form new connections between fungal guilds, genes and function. If a tree falls in the forest — whether or not anyone registers the sound — … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …

… Machine learning methods were applied on sequenced fungal … to identify data generated in part through the 1000 Fungal Genomes Project, including 55 newly-sequenced … Dothideomycetes genomes were conducted as part of the 1000 Fungal Genomes Project supported by the JGI Community …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … natural products of microbial origin is around 30,000 from fungal, and a 40,000 from bacteria. Okay? And among the … why the stereochemistry was that way. And he told me, it’s enzymes. It’s magic.  BEN:  Yeah, right.  DAN: I thought …

… Uncovering associations between plant roots and fungi that can help … other plant-associated fungi. Their analysis identified fungal gene families that help determine if these fungi act … partnerships. To learn more about these other plant-fungal relationships, an international team led by graduate …

… Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s … some of these enormous genes that encode these very large enzymes. And I was like, OK, wow, these are really cool. And … are protecting the plants against pathogens. So usually fungal or oomycete pathogens. In this case they worked on a …