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… Foster and too many others to name at JGI for the last two years or so. SMC is now released and ready for the public to … reminds me almost working with Bill back in the ’50s and ’60s of the golden age of antibiotic discoveries. Everything … you go to the website, which is smc.jgi.doe.gov , the stats page is showing me that right now we have just over a …

… et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you succeed in finding … on the backs of people who’ve done a lot of work over the years. We have a pretty good idea of what the different … is another community effort that’s been built up over the years and is really strong for finding lots of different …

… has a book called The Plant Hunter and I’ve read all 400 pages of her life and I feel like I have a new friend that … And so a path opened itself to me, just before my senior year of college, a chance to go to the Amazon and work with … scientists to think about, because if you look at the 36 hotspots, or terrestrial biodiversity hotspots that we …

… The JGI is represented at conferences year round; find out where our researchers will be …

… we are today, recording today. BRIAN BACHMANN: Yeah, in the year 2000. And I was trying to figure out what to do with … out gene clusters maybe once a month at most. Maybe twice a year, a full gene cluster would come out. And it was a very … And I thought, well, I know that we can do this. So in 2006 was when I started our cave-based natural product …

… soil ecosystem. Microbiome 11, 237. https://doi.org/10.1186/s40168-023-01666-z Neri U., Wolf, Y., Roux S., Camargo A.P., et al. …

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… as a new type of medicine that will open up a new year for targeted anti cancer drug discovery. DAN: Yeah, … drug conjugates, abbreviated as “ADC”, was approved in the year 2000, and utilize the enediyne as the payload. We call … these natural products. So this gives you approximately a 6% successful drug discovery rate.   And this is 100 times …

… advisor.  Brad: Oh my goodness. Those were good years, Dan!  Dan: For too many years. Brad: And now look, you’re like, famous. Dan: Famous? … at the University of Hawaii and moved there in the early ’60s from Berkeley to work on this new budding field of …

… N., Roux, S. et al. Coassembly and binning of a twenty-year metagenomic time-series from Lake Mendota. Sci Data 11 , 966 (2024). https://doi.org/10.1038/s41597-024-03826-8 … Acids Research , Volume 51, Issue D1, 6 January 2023, Pages D723–D732, https://doi.org/10.1093/nar/gkac976 Roux, …

… you can probably skip straight on to Episodes 4 5 and 6, for some fun interviews, unless you want to fact check … been in – working in secondary metabolism for almost 20 years now. Which when I did the math, that was a surprise to … professor at the University of Rhode Island for a couple of years before I left that to join a biotech startup. And …

… 3 of the Primer! — DAN: So, you know, in the in the 50s 60s 70s, most of the exploration of this is done by what’s … natural product molecules might actually get to market in a year. And that would be a good thing. That would be high. … has evolved over, you know, probably – possibly billions of years. And so it is pretty used to the way that the assembly …