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… The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to … metabolomics with genomic data to gain insights into how small molecules function within plants, microbes, and ecosystems. … allows us to uncover globally distributed molecules with conserved structures, offering fresh insights …

… collaborative user projects, the JGI’s Plant Program delves into the natural world’s potential to address global challenges by exploring plants’ role in capturing carbon, detoxifying soils, … bioeconomy where plants are a major source of chemical production and contribute to a healthier planet and a …

… of Natural Prodcast. This week, Alison and I talk to Roger Linington, from Simon Fraser University in British Columbia, … Panama, straight out of my graduate school, and was given a small lab in the National Science Center there and ran this … was very much medicinal chemistry. My job was to make a molecule a day. And one of the things I wanted from that …

… metabolites across bacteria, fungi, algae and plants. These molecules, which are not essential for fundamental growth, provide critical advantages to the organisms producing them, and are often involved in defense, nutrient acquisition and communication. … realized under standard laboratory conditions, with only a small portion of the biosynthetic gene clusters (BGCs) being …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … it just so happens that bacteria make a lot of the kinds of molecules that humans find useful as drugs. So yeah, so … any water that washed down off the hills might carry small pieces of gold along with them and end up in the beds …

… natural products, getting into the ocean and looking for molecules from the very beginning of the field. I learned a … a company, here in La Jolla, called Nereus Pharmaceuticals, small biotech. And that’s a whole other story, biotechs. But … that could afford to do all of the complex biology and production that we couldn’t do. So 2021, we have two drugs …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … great conversations that we’ve already recorded with some excellent scientists, and that’s probably how we’ll continue … like there are there is a big importance on the kind of molecules that they’re sharing and expressing, and that it …

… of Natural Prodcast. A little bit of a bonus episode, since I’m off schedule, but this is an important one that … the normal amount that we get, which is already a fairly small number. We’re a very niche podcast. And so maybe if we … as an undergrad. And to me, looking at the chemistry of the molecules and then looking at how they were made was really …

… The joint Critical Minerals and Materials call represents a unique opportunity … synthesis, metabolomics and analysis will be provided for free to the PI by the Department of Energy’s funding of the … review by JGI staff as well as staff at the other participating facilities, who consider technical feasibility and …

… The Joint Genome Institute and the Molecular Foundry have launched a joint Critical Minerals and Materials proposal call . This represents a … The JGI supports remote users. Users conduct experiments in their own labs or collect field samples. Depending on the …

… community itself works together to elicit new metabolite production. And we are also interested in how the jelly … Dan: Yeah. Well we need more people like you finding the molecules so then we can tie them back to the gene clusters … chemistry but I think that’s not necessarily – There are small molecules that host make as well. And so hosts and …

… Hey everyone. Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society … as a simple organic chemist, can I make that big, beautiful molecule? And so I’d like to think I’ve evolved a bit since … UDWARY: Sure. ALISON NARAYAN: And so we usually start on small scale in the lab. So we’ll run things in like little …