Search

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … right. So I did a PhD in microbiology at MIT, and I studied microbial ecology. I studied Vibrio species in the ocean, so … But where taxol comes from is, from the bark of the yew tree, is where it was originally discovered. And so that …

… Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … associated with the chemistry department as well as the life sciences department. So welcome, Alison to today’s … with. DAN UDWARY: Yeah. ALISON NARAYAN: And there are other tools that I think are really useful, that again are set up …

… of thought with that. So some people are interested in cave microbial– people are interested in the more extreme … ecology, because we feel as though that stacks the deck for discovering molecules that do something. And that’s a whole … an undergraduate and not succeeding and still using all the tools from mechanistic enzymology to natural product …

… and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … advances in management, processing and visualization of “big data,” and artificial Intelligent/machine learning approaches in data … The research efforts of the group have concentrated in demonstrating the power of …

… group and focused on new technologies and optimizing tools — including strain engineering — to make them more … Informatics Group : a team that develops data science tools for workflow management and novel automations for DNA design, assembly and analysis Overview of biodesign products The JGI Biodesign platform enables …

… here today, and we wanted to talk to her about a whole list of things. So we have a Scripps background shared together, … that I’ve appreciated since starting my own group is these tools, in terms of looking at the chemistry produced by … And sometimes, in terms of biological activities– like antimicrobial or something– sometimes a little difference is …

… joined the JGI in 2017, he brought with him 20 years of industry experience — and an opportunity to expand the … Launched in 2025, the initiative aims to accelerate scientific discovery, strengthen national security and ensure … data repositories for genome information with analysis tools for mining and prediction The JGI works in partnership …

… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … little vague to me. What do you mean by putting a bunch of tools in one package? DAN UDWARY: Oh, sure. So if I wanted … of the IMG data portal , which is a larger portal for microbial genomics. IMG stands for Integrated Microbial …

… genomic revolution, to me, as a natural part chemist for microbial natural product, is that I love microbial natural … taxol, for example. If you say isolate compound from the trees – if you’re cutting the trees, it takes years to … collect microorganisms all over the world for the sake of discovering biologically active natural products.  DAN: …

… expertise and infrastructure enable a broad community of scientists and engineers to leverage our data to develop new algorithms, models and tools in support of DOE mission priorities. Data discoverability and … Download plant, algal, fungal and microbial genomes and metagenomes — top-quality genomic …

… So I was always an outdoorsy kid – I was often found in a tree or covered in dirt playing with my dog in the yard. But … get a DNA sequence first. And there are plenty of software tools to find natural product gene clusters, and even be … that we found, indeed, that both formulations had some antimicrobial properties. But the one that was used in …

… group aims at improving our collective understanding of ecological and evolutionary parameters driving virus:host dynamics in environmental microbial communities. This involves both experimental and computational exploration of uncultivated viral diversity, characterization of …