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… little vague to me. What do you mean by putting a bunch of tools in one package? DAN UDWARY: Oh, sure. So if I wanted … of the IMG data portal , which is a larger portal for microbial genomics. IMG stands for Integrated Microbial … bacterial and archaeal orders as seen on the phylogenetic tree, with new lineages of uncultivated genomes from the GEM …

Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … associated with the chemistry department as well as the life sciences department. So welcome, Alison to today’s … with. DAN UDWARY: Yeah. ALISON NARAYAN: And there are other tools that I think are really useful, that again are set up …

… of thought with that. So some people are interested in cave microbial– people are interested in the more extreme … ecology, because we feel as though that stacks the deck for discovering molecules that do something. And that’s a whole … an undergraduate and not succeeding and still using all the tools from mechanistic enzymology to natural product …

… group and focused on new technologies and optimizing tools — including strain engineering — to make them more … Informatics Group : a team that develops data science tools for workflow management and novel automations for DNA design, assembly and analysis Overview of synthesis products The JGI DNA Synthesis platform enables …

… here today, and we wanted to talk to her about a whole list of things. So we have a Scripps background shared together, … that I’ve appreciated since starting my own group is these tools, in terms of looking at the chemistry produced by … And sometimes, in terms of biological activities– like antimicrobial or something– sometimes a little difference is …

… genomic revolution, to me, as a natural part chemist for microbial natural product, is that I love microbial natural … taxol, for example. If you say isolate compound from the trees – if you’re cutting the trees, it takes years to … collect microorganisms all over the world for the sake of discovering biologically active natural products.  DAN: …

… and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … A global metagenomic map of urban microbiomes and antimicrobial resistance. Cell . 184(13):3376-3393 Almeida A, et … of bacterial and archaeal isolates expand coverage of the tree of life.  Nature Biotechnology  35(7):676-683 Schulz …

… … DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger … we’re now very much – we’re interested in how we can build tools which will let us see the whole landscape of natural … to try and create an open source database of all known microbial natural products. So if you think about natural …

So I was always an outdoorsy kid – I was often found in a tree or covered in dirt playing with my dog in the yard. But … get a DNA sequence first. And there are plenty of software tools to find natural product gene clusters, and even be … that we found, indeed, that both formulations had some antimicrobial properties. But the one that was used in …

… of a particular part of the Streptomyces phylogenomic tree, then you will be in a position to say, this group of … I have the feeling that once we have the synthetic biology tools, we finally are in a position to exploit secondary … UGA-Langebio in Irapuato, Mexico. His interests are in microbial diversity and evolution, particularly as how …

… crops. But most available genomes are from narrow swaths of the plant tree of life. One project aims to change that. …

… … DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took … I did my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for … using these together along with all of our computational tools to really build out much more of an integrative …